Studientyp:
Epidemiologische Studie
(Beobachtungsstudie)
Extremely low-frequency magnetic fields and survival from childhood acute lymphoblastic leukemia: an international follow-up study
epidem.
[Extrem niederfrequente Magnetfelder und Überleben bei akuter lymphatischer Leukämie im Kindesalter: eine internationale Follow-Up-Studie]
Von:
Schüz J, Grell K, Kinsey S, Linet MS, Link MP, Mezei G, Pollock BH, Roman E, Zhang Y, McBride ML, Johansen C, Spix C, Hagihara J, Saito AM, Simpson J, Robison LL, Dockerty JD, Feychting M, Kheifets L, Frederiksen K
Veröffentlicht in: Blood Cancer J 2012; 2: e98
Ziel der Studie (lt. Autor)
In einer internationalen Follow-up-Studie wurde der Zusammenhang zwischen der Exposition bei extrem niederfrequenten Magnetfeldern und dem Überleben bei akuter lymphatischer Leukämie im Kindesalter untersucht. Die gepoolte Analyse basierte auf den Daten folgender Studien aus Kanada (McBride et al., 1999), Dänemark (Olsen et al., 1993), Deutschland (Michaelis et al., 1998), Neuseeland (Dockerty et al., 1999), Schweden (Feychting et al., 1993), Großbritannien (UK Childhood Cancer Study Investigators, 1999), USA (Linet et al., 1997), Deutschland (Schüz et al., 2001), Japan (Kabuto et al., 2006) und USA (Foliart et al., 2006).
Weitere Details
Endpunkt/Art der Risikoabschätzung
Exposition
Abschätzung
- Messung: 24-stündige oder längere Messungen
- Berechnung: basierend auf Informationen zur früheren Leitungslast der Hochspannungsfreileitung und ihrer Entfernung zur Wohnung
Expositionsgruppen
|
Gruppe
|
Charakteristik
|
|
Referenzgruppe 1
|
Magnetfeld-Exposition: ≤ 0,1 µT
|
|
Gruppe 2
|
Magnetfeld-Exposition: 0,1 - 0,2 µT
|
|
Gruppe 3
|
Magnetfeld-Exposition: 0,2 - 0,3 µT
|
|
Gruppe 4
|
Magnetfeld-Exposition: > 0,3 µT
|
Population
-
Gruppe:
-
Alter:
1–14 Jahre
-
Merkmale:
Kinder mit akuter lymphatischer Leukämie
-
Beobachtungszeitraum:
unterschiedlich für jedes Land, ab 1988
-
Studienort:
Kanada, Dänemark, Deutschland, Neuseeland, Schweden, USA, Großbritannien, Japan
-
Ausschlusskriterien:
Daten zur Exposition aus der Orginalstudie nicht vorhanden; Gesundheitszustand nicht bekannt; Kind jünger als 1 Jahr bei der Diagnose; Diagnosedatum des Zweittumors unbekannt
Studiengröße
| Typ |
Wert |
| Gesamtzahl |
3.073 |
Statistische Analysemethode:
- Kaplan-Meier-Schätzung
- proportionaler Hazard-Regression nach Cox, Sensitivitätsanalysen
Ergebnisse (lt. Autor)
Studie gefördert durch
-
Electric Power Research Institute (EPRI), USA
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