Studientyp:
Epidemiologische Studie
(Beobachtungsstudie)
A case-control study of childhood leukemia in southern Ontario, Canada, and exposure to magnetic fields in residences
epidem.
[Eine Fall-Kontroll-Studie zu Kinder-Leukämie in Süd-Ontario, Kanada, und der Exposition bei häuslichen Magnetfeldern]
Von:
Green LM, Miller AB, Villeneuve PJ, Agnew DA, Greenberg ML, Li J, Donnelly KE
Veröffentlicht in: Int J Cancer 1999; 82 (2): 161-170
Ziel der Studie (lt. Autor)
Weitere Details
Die Magnetfeld-Exposition wurde durch Punktmessungen innerhalb und außerhalb der Wohnungen sowie durch Wire-code-Klassifizierung nach Wertheimer-Leeper, Barnes (Wertheimer-Leeper-Schema abgeändert durch Berücksichtigung der unterirdischen Verkabelung) und Kaune-Savitz abgeschätzt.
Endpunkt/Art der Risikoabschätzung
Art der Abschätzung:
(Odds Ratio (OR))
Exposition
Abschätzung
Expositionsgruppen
Gruppe
|
Charakteristik
|
Referenzgruppe 1
|
Messung der magnetischen Flussdichte im Kinderzimmer: < 0,03 µT
|
Gruppe 2
|
Messung der magnetischen Flussdichte im Kinderzimmer: 0,03 - 0,06 µT
|
Gruppe 3
|
Messung der magnetischen Flussdichte im Kinderzimmer: 0,06 - 0,12 µT
|
Gruppe 4
|
Messung der magnetischen Flussdichte im Kinderzimmer: ≥ 0,13 µT
|
Referenzgruppe 5
|
Messung der magnetischen Flussdichte in der Wohnung: < 0,04 µT
|
Gruppe 6
|
Messung der magnetischen Flussdichte in der Wohnung: 0,04 - 0,08 µT
|
Gruppe 7
|
Messung der magnetischen Flussdichte in der Wohnung: 0,09 - 0,14 µT
|
Gruppe 8
|
Messung der magnetischen Flussdichte in der Wohnung: ≥ 0,15 µT
|
Referenzgruppe 9
|
Messung der magnetischen Flussdichte außerhalb der Wohnung: < 0,03 µT
|
Gruppe 10
|
Messung der magnetischen Flussdichte außerhalb der Wohnung: 0,03 - 0,07 µT
|
Gruppe 11
|
Messung der magnetischen Flussdichte außerhalb der Wohnung: 0,08 - 0,14 µT
|
Gruppe 12
|
Messung der magnetischen Flussdichte außerhalb der Wohnung: ≥ 0,15 µT
|
Referenzgruppe 13
|
Wertheimer-Leeper: geringe Niederstrom-Konfiguration
|
Gruppe 14
|
Wertheimer-Leeper: normale Niederstrom-Konfiguration
|
Gruppe 15
|
Wertheimer-Leeper: normale Hochstrom-Konfiguration
|
Gruppe 16
|
Wertheimer-Leeper: erhöhte Hochstrom-Konfiguration
|
Referenzgruppe 17
|
Wertheimer-Leeper modifiziert nach Barnes: unterirdische Verkabelung
|
Gruppe 18
|
Wertheimer-Leeper modifiziert nach Barnes: geringe Niederstrom-Konfiguration
|
Gruppe 19
|
Wertheimer-Leeper modifiziert nach Barnes: normale Niederstrom-Konfiguration
|
Gruppe 20
|
Wertheimer-Leeper modifiziert nach Barnes: normale Hochstrom-Konfiguration
|
Gruppe 21
|
Wertheimer-Leeper modifiziert nach Barnes: erhöhte Hochstrom-Konfiguration
|
Referenzgruppe 22
|
Kaune-Savitz: niedrig
|
Gruppe 23
|
Kaune-Savitz: mittel
|
Gruppe 24
|
Kaune-Savitz: hoch
|
Population
-
Gruppe:
-
Alter:
0–14 Jahre
-
Beobachtungszeitraum:
1985 - 1993
-
Studienort:
Kanada (Süd-Ontario)
Fallgruppe
Kontrollgruppe
-
Auswahl:
-
Matching:
- Geschlecht
- Alter
- Fall:Kontrolle = 1:2
Studiengröße
|
Fälle |
Kontrollen |
Anzahl geeignet |
298 |
1.133 |
Teilnehmerzahl |
203 |
419 |
Anzahl auswertbar |
201 |
406 |
Statistische Analysemethode:
- konditionale logistische Regression
(
Anpassung:
)
Ergebnisse (lt. Autor)
Studie gefördert durch
-
Ontario Hydro (Hydro-Electric Power Commission), Canada
Themenverwandte Artikel
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Extremely Low-Frequency Magnetic Fields and the Risk of Childhood B-Lineage Acute Lymphoblastic Leukemia in a City With High Incidence of Leukemia and Elevated Exposure to ELF Magnetic Fields
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