Studientyp:
Epidemiologische Studie
(Beobachtungsstudie)
Residential magnetic fields as a risk factor for childhood acute leukaemia: results from a German population-based case-control study
epidem.
[Häusliche Magnetfelder als Risikofaktor für akute Leukämie bei Kindern: Ergebnisse einer deutschen bevölkerungsbezogenen Fall-Kontroll-Studie]
Von:
Schüz J, Grigat JP, Brinkmann K, Michaelis J
Veröffentlicht in: Int J Cancer 2001; 91 (5): 728-735
Ziel der Studie (lt. Autor)
Weitere Details
Die Magnetfeld-Exposition wurde unter der Matratze des Kinderbetts und im Wohnzimmer über die Zeitdauer von 24 Stunden in der Wohnung gemessen, in der das Kind vor Diagnosestellung am längsten gewohnt hat. Die Exposition wurde in hoch (0,2 µT und mehr) und niedrig (unter 0,2 µT) eingeteilt.
Endpunkt/Art der Risikoabschätzung
Art der Abschätzung:
(Odds Ratio (OR))
Exposition
Abschätzung
- Fragebogen
- Befragung
- Messung: 24-Stunden-Messung unter der Matratze des Kinderbetts und im Wohnzimmer; Punktmessungen; Kurzzeit-Messungen (um Quellen erhöhter Magnetfelder aufzufinden)
- Berechnung: Nacht-Wert (Median der zwischen 20 und 6 Uhr aufgezeichneten Werte), Tages-Wert (Median zwischen 6 und 20 Uhr)
Expositionsgruppen
|
Gruppe
|
Charakteristik
|
|
Referenzgruppe 1
|
Median der 24-Stunden-Messung im Kinderzimmer: < 0,2 µT
|
|
Gruppe 2
|
Median der 24-Stunden-Messung im Kinderzimmer: ≥ 0,2 µT
|
|
Gruppe 3
|
Median der 24-Stunden-Messung im Kinderzimmer: 0,2 < 0,4 µT
|
|
Gruppe 4
|
Median der 24-Stunden-Messung im Kinderzimmer: ≥ 0,4 µT
|
|
Referenzgruppe 5
|
Mittel der 24-Stunden-Messung im Kinderzimmer: < 0,2 µT
|
|
Gruppe 6
|
Mittel der 24-Stunden-Messung im Kinderzimmer: ≥ 0,2 µT
|
|
Gruppe 7
|
Mittel der 24-Stunden-Messung im Kinderzimmer: 0,2 < 0,4 µT
|
|
Gruppe 8
|
Mittel der 24-Stunden-Messung im Kinderzimmer: ≥ 0,4 µT
|
|
Referenzgruppe 9
|
Tages-Wert: < 0,2 µT
|
|
Gruppe 10
|
Tages-Wert: ≥ 0,2 µT
|
|
Gruppe 11
|
Tages-Wert: 0,2 < 0,4 µT
|
|
Gruppe 12
|
Tages-Wert: ≥ 0,4 µT
|
|
Referenzgruppe 13
|
Nacht-Wert: < 0,2 µT
|
|
Gruppe 14
|
Nacht-Wert: ≥ 0,2 µT
|
|
Gruppe 15
|
Nacht-Wert: 0,2 < 0,4 µT
|
|
Gruppe 16
|
Nacht-Wert: ≥ 0,4 µT
|
Population
-
Gruppe:
-
Alter:
0–14 Jahre
-
Beobachtungszeitraum:
a) Oktober 1992 - September 1994, b) Januar 1990 - September 1994
-
Studienort:
West-Deutschland (Umkreis von Kernkraftwerken bis zu 15 km entfernt)
Fallgruppe
Kontrollgruppe
-
Auswahl:
-
Matching:
- Geschlecht
- Region
- Geburtsdatum
Studiengröße
|
Fälle |
Kontrollen |
| Anzahl geeignet |
847 |
2.127 |
| Anzahl kontaktiert |
783 |
2.041 |
| Teilnehmerzahl |
520 |
1.319 |
| Teilnehmerrate |
61 % |
62 % |
| Anzahl auswertbar |
514 |
1.301 |
Statistische Analysemethode:
(
Anpassung:
- Alter
- Geschlecht
- sozioökonomischer Status
- Grad der Verstädterung
)
Ergebnisse (lt. Autor)
Einschränkungen (lt. Autor)
Studie gefördert durch
-
Bundesministerium für Umwelt, Naturschutz und Reaktorsicherheit (Federal Ministry of the Environment, Nature Conservation, and Nuclear Safety), Germany
Themenverwandte Artikel
-
Amoon AT et al.
(2022):
Pooled analysis of recent studies of magnetic fields and childhood leukemia
-
Seomun G et al.
(2021):
Exposure to extremely low-frequency magnetic fields and childhood cancer: A systematic review and meta-analysis
-
Núñez-Enríquez JC et al.
(2020):
Extremely Low-Frequency Magnetic Fields and the Risk of Childhood B-Lineage Acute Lymphoblastic Leukemia in a City With High Incidence of Leukemia and Elevated Exposure to ELF Magnetic Fields
-
Auger N et al.
(2019):
Residential exposure to electromagnetic fields during pregnancy and risk of child cancer: A longitudinal cohort study
-
Crespi CM et al.
(2019):
Childhood leukemia risk in the California Power Line Study: Magnetic fields versus distance from power lines
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Swanson J et al.
(2019):
Changes over time in the reported risk for childhood leukaemia and magnetic fields
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Swanson J et al.
(2018):
Reanalysis of risks of childhood leukaemia with distance from overhead power lines in the UK
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Amoon AT et al.
(2018):
Proximity to overhead power lines and childhood leukaemia: an international pooled analysis
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Kheifets L et al.
(2017):
Residential magnetic fields exposure and childhood leukemia: a population-based case-control study in California
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Crespi CM et al.
(2016):
Childhood leukaemia and distance from power lines in California: a population-based case-control study
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Pedersen C et al.
(2015):
Residential exposure to extremely low-frequency magnetic fields and risk of childhood leukaemia, CNS tumour and lymphoma in Denmark
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Leitgeb N
(2015):
Synoptic Analysis Clarifies Childhood Leukemia Risk from ELF Magnetic Field Exposure
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Ba Hakim AS et al.
(2014):
ELF-EMF correlation study on distance from overhead transmission lines and acute leukemia among children in Klang Valley, Malaysia
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Zhao L et al.
(2014):
Magnetic fields exposure and childhood leukemia risk: a meta-analysis based on 11,699 cases and 13,194 controls
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Sermage-Faure C et al.
(2013):
Childhood leukaemia close to high-voltage power lines--the Geocap study, 2002-2007
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(2012):
Extremely low-frequency magnetic fields and survival from childhood acute lymphoblastic leukemia: an international follow-up study
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Association between Childhood Leukaemia and Exposure to Power-frequency Magnetic Fields in Middle Europe
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Could the geomagnetic field be an effect modifier for studies of power-frequency magnetic fields and childhood leukaemia?
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(2007):
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(2007):
Acute childhood leukemias and exposure to magnetic fields generated by high voltage overhead power lines - a risk factor in Iran
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(2007):
Magnetic field exposure and prognostic factors in childhood leukemia
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Childhood leukemia and magnetic fields in Japan: a case-control study of childhood leukemia and residential power-frequency magnetic fields in Japan
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Magnetic field exposure and long-term survival among children with leukaemia
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Dynamic Kerr effect responses in the TeraHertz range
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Schüz J et al.
(2001):
Childhood acute leukaemia and residential 16.7 Hz magnetic fields in Germany
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A pooled analysis of magnetic fields and childhood leukaemia
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Kleinerman RA et al.
(2000):
Are children living near high-voltage power lines at increased risk of acute lymphoblastic leukemia?
-
UK Childhood Cancer Study Investigators
(2000):
Childhood cancer and residential proximity to power lines
-
Greenland S et al.
(2000):
A pooled analysis of magnetic fields, wire codes, and childhood leukemia. Childhood Leukemia-EMF Study Group
-
Green LM et al.
(1999):
A case-control study of childhood leukemia in southern Ontario, Canada, and exposure to magnetic fields in residences
-
UK Childhood Cancer Study Investigators
(1999):
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-
Angelillo IF et al.
(1999):
Residential exposure to electromagnetic fields and childhood leukaemia: a meta-analysis
-
McBride ML et al.
(1999):
Power-frequency electric and magnetic fields and risk of childhood leukemia in Canada
-
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(1999):
Childhood leukemia and personal monitoring of residential exposures to electric and magnetic fields in Ontario, Canada
-
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(1998):
Electromagnetic field exposures and childhood cancers in New Zealand
-
Michaelis J et al.
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Combined risk estimates for two German population-based case-control studies on residential magnetic fields and childhood acute leukemia
-
Michaelis J et al.
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Childhood leukemia and electromagnetic fields: results of a population-based case-control study in Germany
-
Linet MS et al.
(1997):
Residential exposure to magnetic fields and acute lymphoblastic leukemia in children
-
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(1997):
Electromagnetic Fields and Cancer in Children Residing Near Norwegian High-Voltage Power Lines
-
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(1993):
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