この研究は、オランダの前向きコホート調査において、職業ばく露(調査した因子:溶剤、殺虫剤、金属、超低周波磁界(ELF-MF)、電撃、ジーゼル車排気ガス)が非血管系認知症に関連した死亡リスクに及ぼす影響を分析した。各種の職業ばく露の割り当てには職種ばく露マトリクスを用いた。17.3年間の追跡期間を経て、男性682人、女性870人の症例が得られた。コックスの回帰モデルを用いて分析した。その結果、金属、塩素系溶剤、EMF-MFが、男性の非血管系認知症と正の関連性示したことなどを報告している。
The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →
The association between the occupational exposure to extremely low-frequency magnetic fields, electrical shocks as well as other risk factors and the risk of dementia-related mortality was investigated in the Netherlands Cohort Study. Furthermore, the effects of combined exposure to these occupational agents were studied.
Following a case-cohort approach, a randomly selected subcohort (n=5000) was drawn.
グループ | 説明 |
---|---|
参照集団 1 | magnetic field exposure: background |
集団 2 | magnetic field exposure: low |
集団 3 | magnetic field exposure: high |
参照集団 4 | magnetic field exposure: background |
集団 5 | magnetic field exposure: 1st terzile |
集団 6 | magnetic field exposure: 2nd terzile |
集団 7 | magnetic field exposure: 3rd terzile |
参照集団 8 | electric shock risk: background |
集団 9 | electric shock risk: low |
集団 10 | electric shock risk: high |
タイプ | 値 |
---|---|
合計 | 120,852 |
17.3 years of follow-up
A statistically non-significant association between high occupational exposure to extremely low-frequency magnetic fields and dementia-related mortality was observed in men (OR 1.40, CI 0.92-2.14), but not with cumulative occupational exposure.
A significant association between electrical shocks and dementia-related mortality in women was found (OR 11.11, CI 3.84-32.16). However, this association was only observed among women, and the number of high exposed female cases was very low (approximately 1 % of all female cases). Hence this observation should be interpreted with caution.
The authors conclude that there is only limited support for a possible association between occupational exposure to extremely low-frequency magnetic fields and non-vascular dementia.
このウェブサイトはクッキー(Cookies)を使って、最善のブラウジングエクスペリエンスを提供しています。あなたがこのウェブサイトを継続して使用することで、私たちがクッキーを使用することを許可することになります。