Effect of radiofrequency radiation exposure on mouse skin tumorigenesis initiated by 7,12-dimethybenz[alpha]anthracene med./bio.

[Wirkung von Hochfrequenz-Befeldung auf die Tumor-Entstehung in der Haut von Mäusen, eingeleitet durch 7,12-DMBA]

Ziel der Studie (lt. Autor)

Hintergrund/weitere Details

Endpunkt

• Krebs: Haut-Tumoren

Exposition/Befeldung (teilweise nur auf Englisch)

• • CDMA
  • Mobilfunk
  • PCS

Vollständige Ansicht Kompaktansicht

Methoden Endpunkt/Messparameter/Methodik

• molekulare Biosynthese: Tumorpromotion auf molekularer Ebene (Expression von c-fos und Cyclin D1; Western Blot)
• Zelllebensfähigkeit/Zellteilung/Zellproliferation: Zellproliferation (immunhistochemische Analyse unter Verwendung des "anti-proliferating cell nuclear antigen" (PCNA)-Antikörpers)
• Krebs: Haut-Tumoren (Inzidenz und Häufigkeit); makroskopische Untersuchung; Tumorpromotion (siehe "molekulare Biosynthese"))
• morphologische/histopathologische Veränderungen: histopathologische Untersuchung der Haut-Schnitte (Hämatoxylin-Eosin-Färbung)

Hauptergebnis der Studie (lt. Autor)

Studie gefördert durch

• Ministry of Information and Communication, Korea

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