To study if radiofrequency irradiation has a tumor promoting effect, mice with skin tumorigenesis initiated by DMBA (1000 µg/100 µl acetone/mouse on shaved dorsal skin) were exposed to radiofrequency irradiation
One week after DMBA treatment, the animals were randomized into four equal groups of 20 mice each: sham exposed, 849 MHz-, 1,763 MHz-exposed, and TPA-treated (as positive control) groups.
Exposure | Parameters |
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Exposure 1:
848.5 MHz
Exposure duration:
repeated daily exposure, 45 min on/15 min off/45 min on, 5 days/week for 19 weeks
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Exposure 2:
1,762.5 MHz
Exposure duration:
repeated daily exposure, 45 min on/15 min off/45 min on, 5 days/week for 19 weeks
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|
Mice were randomly divided into four exposure groups: 849 MHz-exposed, 1763 MHz-exposed, sham-exposed and TPA-treated.
Frequency | 848.5 MHz |
---|---|
Type | |
Exposure duration | repeated daily exposure, 45 min on/15 min off/45 min on, 5 days/week for 19 weeks |
Exposure source |
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Chamber | reverberation chamber (2293 x 2296 x 1700 mm³) made of stainless steel and fitted with a mode stirrer for field uniformity |
Sham exposure | A sham exposure was conducted. |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
SAR | 0.4 W/kg | average over mass | measured and calculated | whole body | - |
Frequency | 1,762.5 MHz |
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Type | |
Exposure duration | repeated daily exposure, 45 min on/15 min off/45 min on, 5 days/week for 19 weeks |
Exposure source |
|
---|
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
SAR | 0.4 W/kg | average over mass | measured and calculated | whole body | - |
The results suggest that 849 MHz and 1763 MHz radiofrequency irradiations, similar to those emitted from mobile phones, do not have any tumor promoting effect on skin tumor development in DMBA-initiated mice. Skin tumors were observed only in the TPA-treated positive control group.
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