935 MHz cellular phone radiation. An in vitro study of genotoxicity in human lymphocytes med./bio.

[935 MHz Mobilfunkstrahlung. Eine in vitro-Untersuchung der Genotoxizität an humanen Lymphozyten]

Ziel der Studie (lt. Autor)

Hintergrund/weitere Details

Endpunkt

• Genotoxizität/Mutation: Bildung von Mikronuklei, Chromosomenaberrationen, Komet-Assay, Schwesterchromatid-Austausch

Exposition/Befeldung (teilweise nur auf Englisch)

• • Mobilfunk
  • GSM
• • Ko-Exposition

Vollständige Ansicht Kompaktansicht

Methoden Endpunkt/Messparameter/Methodik

• Genotoxizität/Mutation: DNA-Strangbrüche (alkalischer Komet-Assay); Chromosomenaberrationen, Schwesterchromatid-Austausch (Metaphase-Analyse; Fluoreszenz plus Giemsa-Färbung); Bildung von Mikronuklei (Giemsa-Färbung)
• Zelllebensfähigkeit/Zellteilung/Zellproliferation: Geschwindigkeit des Zellzyklus (Kernteilungsindex (NI+2NII+3NIII+4NIV/N; N ist die gesamte Zellanzahl; NI-NIV die Anzahl der Zellen mit einem bis vier Nuclei))

Hauptergebnis der Studie (lt. Autor)

Studie gefördert durch

• GSM Association, UK/Ireland
• Mobile Manufacturers Forum (MMF), Belgium

Themenverwandte Artikel

• Speit G et al. (2013): Genotoxic effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in HL-60 cells are not reproducible
• Waldmann P et al. (2013): Influence of GSM Signals on Human Peripheral Lymphocytes: Study of Genotoxicity
• Cam ST et al. (2012): Single-strand DNA breaks in human hair root cells exposed to mobile phone radiation
• Perrin A et al. (2010): Evaluation of the co-genotoxic effects of 1800 MHz GSM radiofrequency exposure and a chemical mutagen in cultured human cells
• Hintzsche H et al. (2010): Micronucleus frequency in buccal mucosa cells of mobile phone users
• Zhijian C et al. (2010): Impact of 1.8-GHz radiofrequency radiation (RFR) on DNA damage and repair induced by doxorubicin in human B-cell lymphoblastoid cells
• Franzellitti S et al. (2010): Transient DNA damage induced by high-frequency electromagnetic fields (GSM 1.8GHz) in the human trophoblast HTR-8/SVneo cell line evaluated with the alkaline comet assay
• Gajski G et al. (2009): Radioprotective effects of honeybee venom (Apis mellifera) against 915-MHz microwave radiation-induced DNA damage in wistar rat lymphocytes: in vitro study
• Zhijian C et al. (2009): Influence of 1.8-GHz (GSM) radiofrequency radiation (RFR) on DNA damage and repair induced by X-rays in human leukocytes in vitro
• Sannino A et al. (2009): Human fibroblasts and 900 MHz radiofrequency radiation: evaluation of DNA damage after exposure and co-exposure to 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5h)-furanone (MX)
• Cao Y et al. (2009): 900-MHz microwave radiation enhances gamma-ray adverse effects on SHG44 cells
• Tiwari R et al. (2008): Combinative Exposure Effect of Radio Frequency Signals from CDMA Mobile Phones and Aphidicolin on DNA Integrity
• Korenstein-Ilan A et al. (2008): Terahertz radiation increases genomic instability in human lymphocytes
• Yadav AS et al. (2008): Increased frequency of micronucleated exfoliated cells among humans exposed in vivo to mobile telephone radiations
• Mazor R et al. (2008): Increased levels of numerical chromosome aberrations after in vitro exposure of human peripheral blood lymphocytes to radiofrequency electromagnetic fields for 72 hours
• Speit G et al. (2007): Genotoxic effects of exposure to radiofrequency electromagnetic fields (RF-EMF) in cultured mammalian cells are not independently reproducible
• Ferreira AR et al. (2006): Ultra high frequency-electromagnetic field irradiation during pregnancy leads to an increase in erythrocytes micronuclei incidence in rat offspring
• Verschaeve L et al. (2006): Investigation of co-genotoxic effects of radiofrequency electromagnetic fields in vivo
• Diem E et al. (2005): Non-thermal DNA breakage by mobile-phone radiation (1800 MHz) in human fibroblasts and in transformed GFSH-R17 rat granulosa cells in vitro
• Vijayalaxmi et al. (2005): Controversial cytogenetic observations in mammalian somatic cells exposed to extremely low frequency electromagnetic radiation: a review and future research recommendations
• Vijayalaxmi et al. (2004): Controversial cytogenetic observations in mammalian somatic cells exposed to radiofrequency radiation
• Maes A et al. (2001): Cytogenetic effects of 900 MHz (GSM) microwaves on human lymphocytes
• Maes A et al. (2000): Cytogenetic investigations on microwaves emitted by a 455.7 MHz car phone
• Maes A et al. (1997): Cytogenetic effects of 935.2-MHz (GSM) microwaves alone and in combination with mitomycin C
• Maes A et al. (1996): 954 MHz microwaves enhance the mutagenic properties of mitomycin C