Allgemeine Informationen
Female mice were randomly divided into six treatment groups (50 per group in 8 cages): cage control, sham RF, CW RF, pulsed RF, sham ELF, and ELF. All groups, except cage controls, were at the beginning exposed to 4 Gy ionising radiation delivered in three sub-doses at 1 week intervals.
Frequenz
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50 Hz
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Typ
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Expositionsdauer
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kontinuierlich für 17 Monate
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Expositionsquelle
|
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Kammer
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The animals were housed in groups of six or seven in plastic Macrolon III cages (with aspen chip bedding) that were rotated weekly.
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Aufbau
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The exposure system consisted of a wooden rack with 5 rectangular (0.4 x 1.2 m) coils producing a vertical homogeneous (±5%) magnetic field. The coils at the top and bottom had 15 turns, three middle coils had 10 turns. The vertical distances between the coils were 0.26 m.
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Schein-Exposition
|
Eine Schein-Exposition wurde durchgeführt.
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Frequenz
|
902,5 MHz
|
Typ
|
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Charakteristik
|
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Expositionsdauer
|
täglich wiederholte Exposition, 1,5 h/Tag, 5 Tage/Woche, für 17 Monate
|
Expositionsquelle
|
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Kammer
|
Three identical rectangular waveguides (24.8 x 20 cm, 125 cm long, and 190 cm with adapters) were used for CW, pulsed wave (E3) and sham exposures, respectively.
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Aufbau
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Up to 25 mice per waveguide were individually kept in small acrylic restrainers (32 mm diameter, adjustable length). Average weight phantoms filled with a sugar/salt/water solution [Hartsgrove et al., 1987] were put in the empty places.
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Schein-Exposition
|
Eine Schein-Exposition wurde durchgeführt.
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Zusatzinfo
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The animal positions were randomised before each exposure because the location-dependent SAR variation was ±30%.
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Messgröße |
Wert |
Typ |
Methode |
Masse |
Bemerkungen |
SAR
|
1,5 W/kg
|
Mittelwert
|
bestimmt über Leistungsverlust
|
Ganzkörper
|
1,0-1,8 W/kg
|
Frequenz
|
902,4 MHz
|
Typ
|
|
Charakteristik
|
|
Expositionsdauer
|
täglich wiederholte Exposition, 1,5 h/Tag, 5 Tage/Woche, für 17 Monate
|
Modulationsart
|
gepulst
|
Tastgrad
|
12,5 %
|
Folgefrequenz
|
217 Hz
|
Messgröße |
Wert |
Typ |
Methode |
Masse |
Bemerkungen |
SAR
|
0,35 W/kg
|
Mittelwert
|
bestimmt über Leistungsverlust
|
Ganzkörper
|
0,20-0,45 W/kg
|
Referenzartikel
-
Valberg PA
(1995):
Designing EMF experiments: what is required to characterize "exposure"?
-
Morgan MG et al.
(1992):
Alternative functional relationships between ELF field exposure and possible health effects: report on an expert workshop
-
Hartsgrove G et al.
(1987):
Simulated biological materials for electromagnetic radiation absorption studies