Studientyp:
Epidemiologische Studie
(Beobachtungsstudie)
Occupational extremely low-frequency magnetic field exposure and selected cancer outcomes in a prospective Dutch cohort
epidem.
[Berufliche Exposition bei extrem niederfrequenten Magnetfeldern und ausgewählte Krebs-Arten in einer prospektiven niederländischen Kohorte]
Von:
Koeman T, van den Brandt PA, Slottje P, Schouten LJ, Goldbohm RA, Kromhout H, Vermeulen R
Veröffentlicht in: Cancer Causes Control 2014; 25 (2): 203-214
Ziel der Studie (lt. Autor)
Weitere Details
Endpunkt/Art der Risikoabschätzung
Exposition
Abschätzung
Expositionsgruppen
|
Gruppe
|
Charakteristik
|
|
Referenzgruppe 1
|
Exposition: Hintergrund
|
|
Gruppe 2
|
Exposition: niedrig
|
|
Gruppe 3
|
Exposition: hoch
|
|
Gruppe 4
|
Dauer der Exposition in Jahren
|
|
Referenzgruppe 5
|
kumulative Exposition: Hintergrund
|
|
Gruppe 6
|
kumulative Exposition: 1. Terzil
|
|
Gruppe 7
|
kumulative Exposition: 2. Terzil
|
|
Gruppe 8
|
kumulative Exposition: 3. Terzil
|
Population
-
Gruppe:
-
Alter:
55–69 Jahre
-
Merkmale:
Teilnehmer an der niederländischen Kohortenstudie zu Ernährung und Krebs
-
Beobachtungszeitraum:
1986 - 2003
-
Studienort:
Niederlande
-
Datenquelle:
niederländisches Krebsregister und niederländisches Pathologie-Register
Studiengröße
| Typ |
Wert |
| Gesamtzahl |
120.852 |
Statistische Analysemethode:
- proportionale Hazard-Regression nach Cox
(
Anpassung:
- Bildung
- Rauchen, passives Rauchen, BMI, Alkohol, Verzehr von Gemüse, Früchten, Fisch, Fleisch; Gesamt-Energieaufnahme
)
Ergebnisse (lt. Autor)
Etwa 8 % der Männer und 1 % der Frauen hatten jemals eine Berufstätigkeit mit einer hohen beruflichen Exposition bei extrem niederfrequenten Magnetfeldern.
Es wurden keine erhöhten Risiken für Lungen-Krebs, Brustkrebs und Hirntumor insgesamt noch für die untersuchten Unterarten bei Männern und Frauen beobachtet. Für Leukämie und Lymphom wurde bei Männern, die stark exponiert bei ELF-MF waren (Gruppe 3), ein signifikanter Zusammenhang mit akuter myeloischer Leukämie (HR 2,15; KI 1,06-4,35) und follikulärem Lymphom (HR 2,78; KI 1,00-5,77) gefunden. Bei der kumulativen Exposition bei extrem niederfrequenten Magnetfeldern (Gruppe 8) bei den Männern zeigte sich ein signifikanter positiver Zusammenhang mit follikulärem Lymphom, aber nicht mit akuter myeloischer Leukämie.
Die Autoren schlussfolgern, dass es einige Hinweise auf ein erhöhtes Risiko für akute myeloische Leukämie und follikuläres Lymphom bei Männern mit einer beruflichen Exposition bei extrem niederfrequenten Magnetfeldern gibt.
Studie gefördert durch
Themenverwandte Artikel
-
Carlberg M et al.
(2020):
Case-control study on occupational exposure to extremely low-frequency electromagnetic fields and the association with acoustic neuroma
-
Huss A et al.
(2018):
Occupational extremely low frequency magnetic fields (ELF-MF) exposure and hematolymphopoietic cancers - Swiss National Cohort analysis and updated meta-analysis
-
Carlberg M et al.
(2017):
Case-control study on occupational exposure to extremely low-frequency electromagnetic fields and glioma risk
-
Grundy A et al.
(2016):
Occupational exposure to magnetic fields and breast cancer among Canadian men
-
Talibov M et al.
(2015):
Occupational exposure to extremely low-frequency magnetic fields and electrical shocks and acute myeloid leukemia in four Nordic countries
-
Zhao G et al.
(2014):
Relationship between exposure to extremely low-frequency electromagnetic fields and breast cancer risk: a meta-analysis
-
Turner MC et al.
(2014):
Occupational exposure to extremely low frequency magnetic fields and brain tumour risks in the INTEROCC study
-
Sorahan T
(2014):
Magnetic fields and leukaemia risks in UK electricity supply workers
-
Sorahan T
(2014):
Magnetic fields and brain tumour risks in UK electricity supply workers
-
Sun JW et al.
(2013):
Electromagnetic field exposure and male breast cancer risk: a meta-analysis of 18 studies
-
Chen Q et al.
(2013):
A Meta-Analysis on the Relationship between Exposure to ELF-EMFs and the Risk of Female Breast Cancer
-
Sorahan T
(2012):
Cancer incidence in UK electricity generation and transmission workers, 1973-2008
-
Chen C et al.
(2010):
Extremely low-frequency electromagnetic fields exposure and female breast cancer risk: a meta-analysis based on 24,338 cases and 60,628 controls
-
Kheifets L et al.
(2008):
Occupational electromagnetic fields and leukemia and brain cancer: an update to two meta-analyses
-
Johansen C et al.
(2007):
Risk for leukaemia and brain and breast cancer among Danish utility workers: a second follow-up
-
McElroy JA et al.
(2007):
Occupational Exposure to Electromagnetic Field and Breast Cancer Risk in a Large, Population-Based, Case-Control Study in the United States
-
Karipidis K et al.
(2007):
Occupational exposure to power frequency magnetic fields and risk of non-Hodgkin lymphoma
-
Mester B et al.
(2006):
Occupation and malignant lymphoma: a population based case control study in Germany
-
Nichols L et al.
(2005):
Mortality of UK electricity generation and transmission workers, 1973-2002
-
Forssen UM et al.
(2005):
Occupational magnetic fields and female breast cancer: a case-control study using Swedish population registers and new exposure data
-
Park SK et al.
(2004):
Ecological study on residences in the vicinity of AM radio broadcasting towers and cancer death: preliminary observations in Korea
-
Band PR et al.
(2004):
Identification of Occupational Cancer Risks in British Columbia: A Population-Based Case-Control Study of 769 Cases of Non-Hodgkin's Lymphoma Analyzed by Histopathology Subtypes
-
Willett EV et al.
(2003):
Occupational exposure to electromagnetic fields and acute leukaemia: analysis of a case-control study
-
Bethwaite P et al.
(2001):
Acute leukemia in electrical workers: a New Zealand case-control study
-
van Wijngaarden E et al.
(2001):
Mortality patterns by occupation in a cohort of electric utility workers
-
Bjork J et al.
(2001):
Are occupational, hobby, or lifestyle exposures associated with Philadelphia chromosome positive chronic myeloid leukaemia?
-
Harrington JM et al.
(2001):
Leukaemia mortality in relation to magnetic field exposure: findings from a study of United Kingdom electricity generation and transmission workers, 1973-97
-
Erren TC
(2001):
A meta-analysis of epidemiologic studies of electric and magnetic fields and breast cancer in women and men
-
Savitz DA et al.
(2000):
Case-cohort analysis of brain cancer and leukemia in electric utility workers using a refined magnetic field job-exposure matrix
-
Villeneuve PJ et al.
(2000):
Non-Hodgkin's lymphoma among electric utility workers in Ontario: the evaluation of alternate indices of exposure to 60 Hz electric and magnetic fields
-
Kheifets LI et al.
(1999):
Comparative analyses of the studies of magnetic fields and cancer in electric utility workers: studies from France, Canada, and the United States
-
Floderus B et al.
(1999):
Occupational magnetic field exposure and site-specific cancer incidence: a Swedish cohort study
-
Johansen C et al.
(1998):
Risk of cancer among Danish utility workers - a nationwide cohort study
-
Schroeder JC et al.
(1997):
Lymphoma and multiple myeloma mortality in relation to magnetic field exposure among electric utility workers
-
Feychting M et al.
(1997):
Occupational and residential magnetic field exposure and leukemia and central nervous system tumors
-
Kheifets LI et al.
(1997):
Occupational electric and magnetic field exposure and leukemia. A meta-analysis
-
Kheifets LI et al.
(1997):
Leukemia risk and occupational electric field exposure in Los Angeles County, California
-
Guenel P et al.
(1996):
Exposure to 50-Hz electric field and incidence of leukemia, brain tumors, and other cancers among French electric utility workers
-
Fear NT et al.
(1996):
Cancer in electrical workers: an analysis of cancer registrations in England, 1981-87
-
Miller AB et al.
(1996):
Leukemia following occupational exposure to 60-Hz electric and magnetic fields among Ontario electric utility workers
-
Savitz DA et al.
(1995):
Magnetic field exposure in relation to leukemia and brain cancer mortality among electric utility workers
-
Tynes T et al.
(1994):
Incidence of cancer among workers in Norwegian hydroelectric power companies
-
London SJ et al.
(1994):
Exposure to magnetic fields among electrical workers in relation to leukemia risk in Los Angeles County
-
Theriault G et al.
(1994):
Cancer risks associated with occupational exposure to magnetic fields among electric utility workers in Ontario and Quebec, Canada, and France: 1970-1989
-
Sahl JD et al.
(1993):
Cohort and nested case-control studies of hematopoietic cancers and brain cancer among electric utility workers
-
Guenel P et al.
(1993):
Incidence of cancer in persons with occupational exposure to electromagnetic fields in Denmark
-
Floderus B et al.
(1993):
Occupational exposure to electromagnetic fields in relation to leukemia and brain tumors: a case-control study in Sweden
-
Tynes T et al.
(1992):
Incidence of cancer in Norwegian workers potentially exposed to electromagnetic fields
-
Richardson S et al.
(1992):
Occupational risk factors for acute leukaemia: a case-control study
-
Törnqvist S et al.
(1991):
Incidence of leukaemia and brain tumours in some "electrical occupations"
-
Robinson CF et al.
(1991):
Electromagnetic field exposure and leukemia mortality in the United States
-
Loomis DP et al.
(1990):
Mortality from brain cancer and leukaemia among electrical workers
-
Bastuji-Garin S et al.
(1990):
Acute leukaemia in workers exposed to electromagnetic fields
-
Juutilainen J et al.
(1990):
Incidence of leukaemia and brain tumours in Finnish workers exposed to ELF magnetic fields
-
Pearce NE et al.
(1989):
Case-control studies of cancer in New Zealand electrical workers
-
Linet MS et al.
(1988):
Leukemias and occupation in Sweden: a registry-based analysis
-
Törnqvist S et al.
(1986):
Cancer in the electric power industry
