Expression of HSP72 after ELF-EMF exposure in three cell lines med./bio.

[HSP70-Expression in drei Zelllinien nach ELF-EMF Exposition]

Ziel der Studie (lt. Autor)

Hintergrund/weitere Details

Endpunkt

• molekulare Biosynthese: Hitzeschock-Protein (HSP72)-Expression

Exposition/Befeldung (teilweise nur auf Englisch)

• • 50/60 Hz
  • magnetisches Feld

Vollständige Ansicht Kompaktansicht

Methoden Endpunkt/Messparameter/Methodik

• molekulare Biosynthese: HSP72-Expression (Gen-Transkription und Protein-Expression; spezieller kommerzieller Assay oder "Lab-on-Chip"-basierte Durchflusszytometrie für die Protein-Expression; RT-PCR für mRNA-Expression)

Hauptergebnis der Studie (lt. Autor)

Studie gefördert durch

• nicht angegeben/keine Förderung

Themenverwandte Artikel

• Heredia-Rojas JA et al. (2010): Effect of 60 Hz magnetic fields on the activation of hsp70 promoter in cultured INER-37 and RMA E7 cells
• Mannerling AC et al. (2010): Effects of 50-Hz magnetic field exposure on superoxide radical anion formation and HSP70 induction in human K562 cells
• Rodriguez de la Fuente AO et al. (2009): Effect of 60 Hz electromagnetic fields on the activity of hsp70 promoter: An in vitro study
• Kanitz MH et al. (2007): Investigation of protein expression in magnetic field-treated human glioma cells
• Bernardini C et al. (2007): Effects of 50 Hz sinusoidal magnetic fields on Hsp27, Hsp70, Hsp90 expression in porcine aortic endothelial cells (PAEC)
• Alfieri RR et al. (2006): Increased levels of inducible HSP70 in cells exposed to electromagnetic fields
• Cotgreave IA (2005): Biological stress responses to radio frequency electromagnetic radiation: are mobile phones really so (heat) shocking?
• Malagoli D et al. (2004): 50 Hz magnetic fields activate mussel immunocyte p38 MAP kinase and induce HSP70 and 90
• Coulton LA et al. (2004): Effect of 50 Hz electromagnetic fields on the induction of heat-shock protein gene expression in human leukocytes
• Tokalov SV et al. (2004): Weak electromagnetic fields (50 Hz) elicit a stress response in human cells
• Shi B et al. (2003): Power-line frequency electromagnetic fields do not induce changes in phosphorylation, localization, or expression of the 27-kilodalton heat shock protein in human keratinocytes
• Henderson BR et al. (2003): Expression levels of heat shock protein 60 in human endothelial cells in vitro are unaffected by exposure to 50 Hz magnetic fields
• Zhou J et al. (2002): Gene expression of cytokine receptors in HL60 cells exposed to a 50 Hz magnetic field
• Miyakawa T et al. (2001): Exposure of Caenorhabditis elegans to extremely low frequency high magnetic fields induces stress responses
• Morehouse CA et al. (2000): Exposure to low-frequency electromagnetic fields does not alter HSP70 expression or HSF-HSE binding in HL60 cells
• Junkersdorf B et al. (2000): Electromagnetic fields enhance the stress response at elevated temperatures in the nematode Caenorhabditis elegans
• Miyakoshi J et al. (2000): Suppression of heat-induced HSP-70 by simultaneous exposure to 50 mT magnetic field
• DiCarlo AL et al. (1999): Myocardial protection conferred by electromagnetic fields
• Pipkin JL et al. (1999): Induction of stress proteins by electromagnetic fields in cultured HL-60 cells
• Tsurita G et al. (1999): Effects of exposure to repetitive pulsed magnetic stimulation on cell proliferation and expression of heat shock protein 70 in normal and malignant cells
• Goodman R et al. (1998): Magnetic field stress induces expression of hsp70
• Han L et al. (1998): Application of magnetic field-induced heat shock protein 70 for presurgical cytoprotection
• Balcer-Kubiczek EK et al. (1998): BIGEL analysis of gene expression in HL60 cells exposed to X rays or 60 Hz magnetic fields
• Kang KI et al. (1998): Luciferase activity and synthesis of Hsp70 and Hsp90 are insensitive to 50Hz electromagnetic fields
• Lin H et al. (1997): Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells
• Goodman R et al. (1994): Increased levels of hsp70 transcripts induced when cells are exposed to low frequency electromagnetic fields
• Goodman R et al. (1989): Exposure of human cells to low-frequency electromagnetic fields results in quantitative changes in transcripts
• Goodman R et al. (1988): Exposure of salivary gland cells to low-frequency electromagnetic fields alters polypeptide synthesis