Studientyp:
Medizinische/biologische Studie
(experimentelle Studie)
Effects of continuous and intermittent exposure to RF fields with a wide range of SARs on cell growth, survival, and cell cycle distribution
med./bio.
[Wirkungen kontinuierlicher und intermittierender Exposition mit Hochfrequenz-Feldern mit einer großen Bandbreite an SAR-Werten auf Zellwachstum, -überleben und Zellzyklus-Verteilung]
Von:
Takashima Y, Hirose H, Koyama S, Suzuki Y, Taki M, Miyakoshi J
rectangular, 110 mm wide x 55 mm high x 310 mm long, operating in TE10 mode
Kammer
The exposure unit was mounted in an incubator.
Aufbau
A culture dish in which the medium stood 8 mm high was placed on two slits in the top wall of the waveguide. The slits were optimized with a pinched shape to increase the effective exposure area and enhance the uniformity of the electric field and the SAR distribution in the medium. One end of the waveguide was terminated with a short-circuiting plate to generate standing waves.
The temperatures of the medium at the maximum SAR position measured using a fibre optic thermometer rose to 39.1 °C, 41.0 °C, and 44.1 °C after exposure to 50, 100, and 200 W/kg, respectively, for 2 h at an ambient temperature of 37 °C. Cells for raised temperature control were incubated at 39, 40, 41, 42, 43, and 44 °C in a conventional incubator for the same time periods.
Ministry of Internal Affairs and Communications, Japan
Themenverwandte Artikel
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Esmekaya MA et al.
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Investigation of the effects of 2.1 GHz microwave radiation on mitochondrial membrane potential (DeltaPsim), apoptotic activity and cell viability in human breast fibroblast cells
Liu YX et al.
(2012):
Exposure to 1950-MHz TD-SCDMA Electromagnetic Fields Affects the Apoptosis of Astrocytes via Caspase-3-Dependent Pathway
Trillo MA et al.
(2011):
Cytostatic response of NB69 cells to weak pulse-modulated 2.2 GHz radar-like signals
Lee KY et al.
(2011):
Effects of combined radiofrequency radiation exposure on the cell cycle and its regulatory proteins
Hoyto A et al.
(2008):
Radiofrequency radiation does not significantly affect ornithine decarboxylase activity, proliferation, or caspase-3 activity of fibroblasts in different physiological conditions
Lee JJ et al.
(2008):
Acute radio frequency irradiation does not affect cell cycle, cellular migration, and invasion
Vijayalaxmi
(2006):
Cytogenetic studies in human blood lymphocytes exposed in vitro to 2.45 GHz or 8.2 GHz radiofrequency radiation
Lantow M et al.
(2006):
Comparative study of cell cycle kinetics and induction of apoptosis or necrosis after exposure of human mono mac 6 cells to radiofrequency radiation
Pavicic I et al.
(2006):
Comparison of 864 MHz and 935 MHz microwave radiation effects on cell culture
Hirose H et al.
(2006):
Phosphorylation and gene expression of p53 are not affected in human cells exposed to 2.1425 GHz band CW or W-CDMA modulated radiation allocated to mobile radio base stations
Merola P et al.
(2006):
Proliferation and apoptosis in a neuroblastoma cell line exposed to 900 MHz modulated radiofrequency field
Yao K et al.
(2004):
Low power microwave radiation inhibits the proliferation of rabbit lens epithelial cells by upregulating P27Kip1 expression
Kwee S et al.
(1998):
Changes in cell proliferation due to environmental non-ionizing radiation 2. Microwave radiation
Stagg RB et al.
(1997):
DNA synthesis and cell proliferation in C6 glioma and primary glial cells exposed to a 836.55 MHz modulated radiofrequency field
Vijayalaxmi et al.
(1997):
Proliferation and cytogenetic studies in human blood lymphocytes exposed in vitro to 2450 MHz radiofrequency radiation
Cleary SF et al.
(1996):
Effects of isothermal 2.45 GHz microwave radiation on the mammalian cell cycle: comparison with effects of isothermal 27 MHz radiofrequency radiation exposure
Cleary SF et al.
(1990):
Glioma proliferation modulated in vitro by isothermal radiofrequency radiation exposure
Rotkovska D et al.
(1987):
Effects of microwaves on the colony-forming capacity of haemopoietic stem cells in mice
Brown RF et al.
(1986):
Differentiation of murine erythroleukemic cells during exposure to microwave radiation
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