疫学研究 (observational study)

[携帯電話基地局周辺地域での臨床的に定義された非特異的症状：後ろ向きの前後比較研究] epidem.

Clinically defined non-specific symptoms in the vicinity of mobile phone base stations: A retrospective before-after study

著者: Baliatsas C, van Kamp I, Bolte J, Kelfkens G, van Dijk C, Spreeuwenberg P, Hooiveld M, Lebret E, Yzermans J

掲載誌: Sci Total Environ 2016; 565: 714-720

この研究は、携帯電話基地局（MPBS）設置が増加する前（T0）と後（T1）の時点でのMPBSばく露関連の非特異的症状（NSS）の有症率および発症数を比較する後ろ向きコホート調査を実施した。オランダの異なる地域にある9つの一般診療科（GP）に登録された1069人の調査参加者の電子カルテ記録に基づきNSSデータを取得した。全ての参加者が最寄りの基地局から500m以内に居住しており、そのうち、T1時点でMPBSへの過敏性を自己申告した55人をMPBS過敏群とした。伝搬モデルと質問票データを併用して、T1時点のMPBSによるRF-EMFへの屋内ばく露を推定した。同様にT0時点のアンテナ数に基づきT0時点の屋内ばく露を推定した。結果として、アンテナ数は前後で>30%の増加であった；MPBS過敏群ではほとんどのNSSの有症率がT0に比べT1時点で高かった；全参加者では、ばく露推定値はGP登録のNSSに関連しなかった；NSSリスクに関して、ばく露とMPBS過敏性との間に交互作用が見られた；臨床的に定義された症状、>6年の時間差を用いた場合、MPBSへのRF-EMFばく露はNSSの発症とは関連しないことが示された、と報告している。

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研究の目的(著者による)

A retrospective cohort study was conducted in the Netherlands to test possible changes in prevalence and number of non-specific symptoms in relation to exposure to mobile phone base stations before and after increase of installed antennas at mobile phone base stations.

詳細情報

Data for the baseline period (January - December 2004) were collected retrospectively for the study population of the cross-sectional study by Baliatsas et al. (2015). Inclusion criteria were availability of complete electronic health record data, comparability of symptom data in terms of registration methodology and living in the same house in 2004 and 2011.
Categorization into sensitivity to mobile phone base stations was based on the reports of the participants in 2011.

影響評価項目／リスク推定のタイプ

不快症状: 23 symptoms such as headache, fatigue, dizziness, memory or concentration problems, skin symptoms, heart palpitations, ear symptoms, neck or shoulder symptoms, back pain, muscular pain
睡眠障害
過敏症

リスク推定のタイプ:

有病率

ばく露

- 移動体通信システム
- 携帯電話基地局
- GSM
- UMTS
- 住宅環境の

ばく露評価

計算: electric field strength was calculated for each participant including all base stations within a 500 m radius of the house and data provided by the Radio Communications Agency Netherlands

調査対象集団

グループ:
- 男性
- 女性
年齢: ≥ 18年
特性: residents living in a radius of 500 m to a base station
観察期間: January - December 2004, follow-up July 2010 - June 2011
調査地域: Netherlands

調査規模

タイプ	値
合計	5,933
評価可能	1,069

統計学的分析方法:

ロジスティック回帰
ポアソン回帰モデル

(調整:

年齢
性別
house ownership status

)

結論(著者による)

Overall 55 participants reported to be electrosensitive to mobile phone base stations in 2011.
There was an increase in the total number of antennas at mobile phone base stations of 30% in the period 2004-2011. Mean total calculated electric field strength was 0.10 (±0.15) V/m in 2004 and 0.104 (±0.15) in 2011 for the electrosensitive group; for the rest of the sample mean exposure levels were 0.11 (±0.23) V/m and 0.12 (±0.23) V/m respectively.
A higher prevalence for most non-specific symptoms was observed in the electrosensitive group in 2011 compared to baseline. Exposure estimates were not associated with general practitioner registered non-specific symptoms in the total sample. However, some significant interactions were observed between electrosensitivity and exposure estimates on risk of symptoms.
The authors concluded that by using clinically defined outcomes and a time difference of 6 years it was demonstrated that radiofrequency electromagnetic field exposure to mobile phone base stations was not associated with the development of non-specific symptoms. Nonetheless, there was some indication for a higher risk of non-specific symptoms for the electrosensitive group, mainly in relation to exposure to UMTS, but this should be interpreted with caution.

研究助成

ZonMw, The Netherlands