この研究は、SD雄ラット(240匹)の免疫系に対する2種類の無線周波電磁界(CDMAおよびWCDMA)の同時組み合わせばく露の影響を調べた。ばく露は1日45 分間、週5日で最長8週間継続した。実験は、同時ばく露群(CDMA、WCDMAそれぞれのSAR 2.0 W/kgで合計4.0 W/kg)・CDMA ばく露群(CDMA単独で4.0 W/kg)・擬似ばく露群をそれぞれ80匹とし、ばく露開始から2週間毎に20匹ずつ屠殺して、血液学的項目、脾臓のCD4+、CD8+、IgM+細胞数、血漿中の種々のサイトカインレベル、mRNA発現レベルなどを測定した。その結果、今回のばく露条件での同時組み合わせばく露は各種の免疫パラメータに影響しなかったと報告している。
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To assess the effect of simultaneous exposure to two types of radiofrequency electromagnetic field signals (CDMA and W-CDMA) on the immune system of rats.
240 rats were used. Every two weeks after the start of the experiment, 20 rats were autopsied.
ばく露 | パラメータ |
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ばく露1:
848.5 MHz
ばく露時間:
continuous for 45 min/day, 5 days/week for up to 8 weeks
|
|
ばく露2:
848.5–1,950 MHz
ばく露時間:
continuous for 45 min/day, 5 days/week for up to 8 weeks
|
Rats were exposed to CDMA alone or simulatenously to CDMA and W-CDMA.
周波数 | 848.5 MHz |
---|---|
タイプ |
|
ばく露時間 | continuous for 45 min/day, 5 days/week for up to 8 weeks |
ばく露の発生源/構造 |
|
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チャンバの詳細 | reverberation chamber (2,295 mm x 2,293 mm x 1,470 mm; thickness of the stainless steel walls 2.3 mm) |
ばく露装置の詳細 | 5 cages were placed on the table located inside the exposure chamber; rats (two rats per cage) were housed in polycarbonate cages (420 x 260 x 180 mm) on hardwood bedding |
Sham exposure | A sham exposure was conducted. |
Additional information | position of the cages and turn of exposure (morning or afternoon) were changed every day |
測定量 | 値 | 種別 | Method | Mass | 備考 |
---|---|---|---|---|---|
SAR | 4 W/kg | average over mass | 計算値 | whole body | - |
周波数 | 848.5–1,950 MHz |
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タイプ |
|
ばく露時間 | continuous for 45 min/day, 5 days/week for up to 8 weeks |
ばく露の発生源/構造 |
|
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Sham exposure | A sham exposure was conducted. |
The data suggest that simultaneous exposure to CDMA and W-CDMA signals with a total SAR dose of 4 W/kg for 45 min/day for 8 weeks, which is a relatively high SAR level compared to the exposure levels for the human system recommended by ICNIRP, did not have any detectable effects on immune function in rats.
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