この研究は、マウスの腫瘍壊死因子(TNF)産生および免疫応答に対するマイクロ波ばく露の影響を調べた。ばく露に用いたマイクロ波は、周波数8.15-18 GHz (1 Hz以内)、電力密度1μW/ cm2で、5時間の全身ばく露を1回実施した。その結果、ばく露により、腹腔マクロファージおよび脾臓T細胞でのTNF産生が有意に増加した;ばく露後に、Tリンパ球での分裂促進反応が増加した;細胞性免疫の活性化はばく露後3日以内に観察された;脂溶性栄養素(ベータカロチン、アルファトコフェロール、ユビキノンQ9)を含む食餌を与えると、ばく露マウスのマクロファージおよびT細胞の活性が上昇した、と報告している。
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To study the effect of weak 8.15-18 GHz microwaves on the tumor necrosis factor secretion and immune response. The aim of the study was to elucidate whether there is a synergism of the immunostimulating effects of low-intensity microwaves and antioxidants (beta-carotene, alpha-tocopherol, and ubiquinone Q9 were given daily with food prior to microwave exposure).
ばく露 | パラメータ |
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ばく露1:
8.15–18 GHz
ばく露時間:
continuous for 5 h
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All details on irradiation described in the reference article
周波数 | 8.15–18 GHz |
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タイプ |
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ばく露時間 | continuous for 5 h |
Additional information | Animals (n=100) were divided in the following manner: n=40 control-cage mice, n=40 antioxidants-fed mice, n=20 sham exposed mice. Half of control-cage and antioxidants-fed groups were exposed to microwave irradiation. |
ばく露の発生源/構造 |
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Sham exposure | A sham exposure was conducted. |
測定量 | 値 | 種別 | Method | Mass | 備考 |
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電力密度 | 1 µW/cm² | - | - | - | - |
A single 5 h exposure induced a significant increase in tumor necrosis factor production in peritoneal macrophages and splenic T cells. The mitogenic response in T lymphocytes increased after microwave exposure. The activation of cellular immunity was revealed within 3 days after irradiation. The diet containing antioxidant nutrients increased the activity of macrophages and T cells from exposed animals.
These data demonstrate that irradiation with low-power density microwaves stimulates the immune potential of macrophages and T cells. The antioxidant treatment enhances the effect of microwaves, in particular at later terms, when the effect of irradiation is reduced.
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