研究のタイプ: 医学／生物学の研究 (experimental study)

[CDMAとWCDMAの無線周波数電磁界へ複合ばく露した妊娠マウスに催奇形性は見られず] med./bio.

Lack of teratogenicity after combined exposure of pregnant mice to CDMA and WCDMA radiofrequency electromagnetic fields

著者: Lee HJ, Lee JS, Pack JK, Choi HD, Kim N, Kim SH, Lee YS
掲載誌: Radiat Res 2009; 172 (5): 648-652
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この論文は、妊娠マウスにCDMAとWCDMAの無線周波数電磁界のを同時に2種類の信号のばく露を同時に与えた。全妊娠期間にわたり、15分の間隔をおいて2回の45分間のばく露を毎日与え、その全身SARは、それぞれの信号について2.0 W/kgであった。その結果、胎仔に何も有害な影響は観察されなかったと結論している。

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研究目的（著者による）

To study the teratogenic effects of multi-signal radiofrequency electromagnetic fields on mouse fetuses.

詳細情報

Pregnant mice were divided into different groups: 1) sham exposed CDMA control mice, 2) CDMA-exposed mice, 3) sham exposed CDMA + WCDMA control mice and 4) CDMA + WCDMA simultaneously exposed mice. Mice received two 45 min radiofrequency field exposures, separated by a 15 minutes interval, daily throughout the entire gestation period. The mice were killed on the 18th day of gestation and fetuses were examined.
A relatively high SAR was used because if adverse effects in mice fetus were not detected at this SAR, realistic radiofrequency field exposures are unlikely to affect humans.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 848.5 MHz
ばく露時間: continuous 2 times 45 min/day, separated by 15 min, throughout gestation (17 days)
CDMA
  • 電界強度: 176.36 V/m effective value (73.1 V/m - 176.36 V/m)
  • SAR: 4.04 W/kg average over mass (whole body) (0.69 W/kg - 4.04 W/kg)
  • SAR: 2 W/kg average over mass (whole body) (at P = 30 W)
  • 電力: 60 W maximum
ばく露2: 1,950 MHz
ばく露時間: 2 times 45 min/d, separated by 15 min, throughout gestation (17 days)
WCDMA
  • 電界強度: 162.5 V/m effective value (64.17 V/m - 162.5 V/m)
  • SAR: 7.13 W/kg average over mass (whole body) (1.11 W/kg - 7.13 W/kg)
  • SAR: 2 W/kg average over mass (whole body) (at P = 18 W)
  • 電力: 60 W maximum

ばく露1

主たる特性
周波数 848.5 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous 2 times 45 min/day, separated by 15 min, throughout gestation (17 days)
Additional information CDMA
ばく露装置
ばく露の発生源／構造
  • patch antenna
チャンバの詳細 2295 mm x 2293 mm x 1470 mm reverberation chamber
Sham exposure A sham exposure was conducted.
パラメータ
測定量 値 種別 Method Mass 備考
電界強度 176.36 V/m effective value 測定値 - 73.1 V/m - 176.36 V/m
SAR 4.04 W/kg average over mass 計算値 whole body 0.69 W/kg - 4.04 W/kg
SAR 2 W/kg average over mass 計算値 whole body at P = 30 W
電力 60 W maximum - - -

ばく露2

主たる特性
周波数 1,950 MHz
タイプ
  • electromagnetic field
ばく露時間 2 times 45 min/d, separated by 15 min, throughout gestation (17 days)
Additional information WCDMA
ばく露装置
ばく露の発生源／構造
  • E1と同じ装置
Sham exposure A sham exposure was conducted.
パラメータ
測定量 値 種別 Method Mass 備考
電界強度 162.5 V/m effective value 測定値 - 64.17 V/m - 162.5 V/m
SAR 7.13 W/kg average over mass 計算値 whole body 1.11 W/kg - 7.13 W/kg
SAR 2 W/kg average over mass 計算値 whole body at P = 18 W
電力 60 W maximum - - -

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露前
  • ばく露後

研究の主なアウトカム（著者による）

Simultaneous experimental exposure to CDMA and WCDMA radiofrequency electromagnetic fields did not cause any observable adverse effects on mouse fetuses.

研究の種別:

研究助成

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