Studientyp:
Medizinische/biologische Studie
(experimentelle Studie)
Exposure to an Extremely-Low-Frequency Magnetic Field Stimulates Adrenal Steroidogenesis via Inhibition of Phosphodiesterase Activity in a Mouse Adrenal Cell Line
med./bio.
[Exposition bei einem extrem niederfrequenten Magnetfeld stimuliert die adrenale Steroidogenese durch die Inhibierung der Phosphodiesterase-Aktivität in einer Nebennieren-Zelllinie der Maus]
Von:
Kitaoka K, Kawata S, Yoshida T, Kadoriku F, Kitamura M
Veröffentlicht in: PLoS One 2016; 11 (4): e0154167-
the exposure apparatus consisted of a cylindrical plastic (polyvinyl chloride) container (37 cm outer diameter, 34.5 cm inner diameter, 33 cm length) placed vertically with a coil inside; the coil consisted of one primary coil and two secondary coils that were placed on the upper and lower ends of the primary coil; coils were made of enameled wires (2.12 mm diameter); for the primary coil, the wire was wound 150 times around the plastic container; for the two secondary coils, the wire was wound 33 times around every layer to correct the uneven distribution of the magnetic flux density of the primary coil; a plastic incubator (25 cm length, 20 cm width and 10 cm height) containing the culture dishes was placed in the middle of each plastic container; to maintain the temperature of 37 ± 0.5°C and 5% CO2 in the incubator, warm water (40 ± 0.5°C) and 5% CO2 air were supplied in the container; the temperature difference between ELF-MF and sham exposure apparatuses was maintained within ± 0.5°C
sham exposure was performed simultaneously with exposure using a sham apparatus, which was made using the same materials with the same size, except for the coil
Soda A et al.
(2008):
Effect of exposure to an extremely low frequency-electromagnetic field on the cellular collagen with respect to signaling pathways in osteoblast-like cells
Japan Society for the Promotion of Science (JSPS), Japan
Themenverwandte Artikel
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(2013):
Chronic exposure to an extremely low-frequency magnetic field induces depression-like behavior and corticosterone secretion without enhancement of the hypothalamic-pituitary-adrenal axis in mice
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(2010):
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(2002):
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(1997):
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Picazo ML et al.
(1996):
Changes in mouse adrenalin gland functionality under second-generation chronic exposure to ELF magnetic fields. I. males
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