Gene expression changes in human cells after exposure to mobile phone microwaves med./bio.

[Genexpressions-Veränderungen in humanen Zellen nach Exposition bei Mobilfunk-Mikrowellen]

Ziel der Studie (lt. Redakteur)

Hintergrund/weitere Details

Endpunkt

• molekulare Biosynthese: Genexpression

Exposition/Befeldung (teilweise nur auf Englisch)

• • Mikrowellen
• • Mobilfunk
  • digitales Mobiltelefon
  • GSM

Vollständige Ansicht Kompaktansicht

Methoden Endpunkt/Messparameter/Methodik

• molekulare Biosynthese: Genexpression (Human Unigene RZPD-2 cDNA Array (DNA-Microarray))

Hauptergebnis der Studie (lt. Autor)

Studie gefördert durch

• Bundesministerium für Bildung und Forschung (BMBF; Federal Ministry for Education and Research), Germany
• European Union (EU)/European Commission
• VERUM Foundation (Stiftung für Verhalten und Umwelt), Germany

Themenverwandte Artikel

• Kayhan H et al. (2016): Does MW Radiation Affect Gene Expression, Apoptotic Level, and Cell Cycle Progression of Human SH-SY5Y Neuroblastoma Cells?
• Zhijian C et al. (2013): Studying the protein expression in human B lymphoblastoid cells exposed to 1.8-GHz (GSM) radiofrequency radiation (RFR) with protein microarray
• Trivino Pardo JC et al. (2012): Microwave electromagnetic field regulates gene expression in T-lymphoblastoid leukemia CCRF-CEM cell line exposed to 900 MHz
• Fragopoulou AF et al. (2012): Brain proteome response following whole body exposure of mice to mobile phone or wireless DECT base radiation
• Sakurai T et al. (2011): Analysis of gene expression in a human-derived glial cell line exposed to 2.45 GHz continuous radiofrequency electromagnetic fields
• Roux D et al. (2011): Human keratinocytes in culture exhibit no response when exposed to short duration, low amplitude, high frequency (900 MHz) electromagnetic fields in a reverberation chamber
• Sekijima M et al. (2010): 2-GHz band CW and W-CDMA modulated radiofrequency fields have no significant effect on cell proliferation and gene expression profile in human cells
• Nylund R et al. (2009): Proteomic Analysis of the Response of Human Endothelial Cell Line EA.hy926 to 1800 GSM Mobile Phone Radiation
• Del Vecchio G et al. (2009): Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells
• Nittby H et al. (2008): Exposure to radiation from global system for mobile communications at 1,800 MHz significantly changes gene expression in rat hippocampus and cortex
• Valbonesi P et al. (2008): Evaluation of HSP70 expression and DNA damage in cells of a human trophoblast cell line exposed to 1.8 GHz amplitude-modulated radiofrequency fields
• Karinen A et al. (2008): Mobile phone radiation might alter protein expression in human skin
• Paparini A et al. (2008): No evidence of major transcriptional changes in the brain of mice exposed to 1800 MHz GSM signal
• Sanchez S et al. (2008): Effect of GSM-900 and -1800 signals on the skin of hairless rats. III: Expression of heat shock proteins
• Buttiglione M et al. (2007): Radiofrequency radiation (900 MHz) induces Egr-1 gene expression and affects cell-cycle control in human neuroblastoma cells
• Chauhan V et al. (2007): Analysis of gene expression in two human-derived cell lines exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field
• Sanchez S et al. (2007): In Vitro Study of the Stress Response of Human Skin Cells to GSM-1800 Mobile Phone Signals Compared to UVB Radiation and Heat Shock
• Zhao R et al. (2007): Studying gene expression profile of rat neuron exposed to 1800 MHz radiofrequency electromagnetic fields with cDNA microassay
• Zhao TY et al. (2007): Exposure to cell phone radiation up-regulates apoptosis genes in primary cultures of neurons and astrocytes
• Friedman J et al. (2007): Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies
• Bundesamt für Strahlenschutz (BfS) (2006): Stellungnahme zum Abschlussbericht des REFLEX-Forschungsverbundes (5. EU-Rahmenprogramm)
• Whitehead TD et al. (2006): The number of genes changing expression after chronic exposure to Code Division Multiple Access or Frequency DMA radiofrequency radiation does not exceed the false-positive rate
• Leszczynski D et al. (2006): Questions and answers concerning applicability of proteomics and transcriptomics in EMF research
• Zeng Q et al. (2006): Effects of global system for mobile communications 1800 MHz radiofrequency electromagnetic fields on gene and protein expression in MCF-7 cells
• Nylund R et al. (2006): Mobile phone radiation causes changes in gene and protein expression in human endothelial cell lines and the response seems to be genome- and proteome-dependent
• Chauhan V et al. (2006): Analysis of proto-oncogene and heat-shock protein gene expression in human derived cell-lines exposed in vitro to an intermittent 1.9 GHz pulse-modulated radiofrequency field
• Qutob SS et al. (2006): Microarray gene expression profiling of a human glioblastoma cell line exposed in vitro to a 1.9 GHz pulse-modulated radiofrequency field
• Belyaev IY et al. (2006): Exposure of rat brain to 915 MHz GSM microwaves induces changes in gene expression but not double stranded DNA breaks or effects on chromatin conformation
• Nikolova T et al. (2005): Electromagnetic fields affect transcript levels of apoptosis-related genes in embryonic stem cell-derived neural progenitor cells
• Czyz J et al. (2004): High frequency electromagnetic fields (GSM signals) affect gene expression levels in tumor suppressor p53-deficient embryonic stem cells
• Nylund R et al. (2004): Proteomics analysis of human endothelial cell line EA.hy926 after exposure to GSM 900 radiation
• Leszczynski D et al. (2004): Applicability of discovery science approach to determine biological effects of mobile phone radiation
• Leszczynski D et al. (2002): Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: Molecular mechanism for cancer- and blood-brain barrier-related effects
• Pacini S et al. (2002): Exposure to global system for mobile communication (GSM) cellular phone radiofrequency alters gene expression, proliferation, and morphology of human skin fibroblasts
• Leszczynski D (2001): Mobile phones, precautionary principle, and future research