この論文は、ラットの精巣機能のうちでも特に感受性が高いと思われる精子形成過程に対するCDMAおよびWCDMA電磁界への同時複合ばく露の影響を調べた。ばく露は45 分/日、5 日/週で12週間行い、CDMAおよびWCDMAによる全身平均SARはそれぞれ2.0 W/kg で、合計4.0 W/kg であった。このような複合ばく露の結果、ラットの精子形成に対する観察可能な有害影響はなかったと結論している。
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To study the effects of combined exposure to radiofrequency electromagnetic fields (WCDMA and CDMA) on rat testicular function (specifically with respect to spermatogenesis).
50 male rats were used, randomly assigned to four groups: a cage control (n=5), a sham exposed control (n=20), a combined radiofrequency-exposed (n=20) or a gamma ray-exposed group (as positive control, 5 Gy, n= 5).
ばく露 | パラメータ |
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ばく露1:
848.5–1,950 MHz
ばく露時間:
continuous 45 min/day, 5 days/week for 12 weeks
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rats were treated in four groups: i) cage control ii) sham exposure iii) RF exposure iv) exposure to gamma rays
ばく露の発生源/構造 |
|
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チャンバの詳細 | 2295 mm x 2293 mm x 1470 mm reverberation chamber with 2.3 mm thick stainless steel walls as exposure chamber |
ばく露装置の詳細 | five 420 mm x 260 mm x 180 mm polycarbonate cages with two rats each placed inside the reverberation chamber; rats exposed simultaneously to WCDMA and CDMA |
Sham exposure | A sham exposure was conducted. |
No significant differences in testicular function, including sperm counts in the cauda epididymis, MDA concentration in testes and epididymis, frequency of spermatogenesis stages, or number of apoptotic cells in each testis, were found during spermatogenesis in rats simultaneously exposed to CDMA and WCDMA radiofrequency electromagnetic fields at a SAR of 2 W/kg each (4 W/kg total) for 12 weeks.
The authors conclude, that the findings suggest that simultaneous exposure to 848.5 MHz and 1950 MHz radiofrequency electromagnetic fields had no adverse effects on the male reproductive system, as seen in this rat spermatogenesis model.
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