この論文は、TEMで発生させた900MHzのGSM信号(SARは1 W/kg)に最大144時間の連続ばく露させた神経細胞のバイアビリティ、増殖、脆弱性を調べた。実験に用いた細胞は、SN56コリン作動性細胞株とラット由来の初代培養皮質ニューロンである。その結果、神経毒性物質との複合ばく露なと特定の条件下においてのみ、GSM変調900MHzへのばく露が神経細胞の酸化的損傷の共ストレッサとして働くことが示唆されたと結論している。
The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →
To study whether prolonged exposure to 900 MHz GSM modulated electromagnetic fields affects viability and vulnerability of two neural cell cultures: primary cortical neurons (primary culture) and SN56 cell line, co-exposed to 25-35AA beta-amyloid (as in vitro model for Alzheimer disease), to glutamate (as model for excitotoxicity) and to H2O2 (as model for oxidative stress).
The two cell cultures were exposed/co-exposed at different time points (after seeding) and for different durations.
ばく露 | パラメータ |
---|---|
ばく露1:
900 MHz
Modulation type:
pulsed
ばく露時間:
up to 144 h
|
|
周波数 | 900 MHz |
---|---|
タイプ |
|
ばく露時間 | up to 144 h |
Modulation type | pulsed |
---|---|
Repetition frequency | 217 Hz |
ばく露の発生源/構造 | |
---|---|
ばく露装置の詳細 | thin inner conductor in the TEM cell provided two symmetrical large regions with field homogeneity; TEM cell placed inside an incubator |
Sham exposure | A sham exposure was conducted. |
測定量 | 値 | 種別 | Method | Mass | 備考 |
---|---|---|---|---|---|
SAR | 1 W/kg | - | - | - | - |
The data showed that radiofrequency exposure did not change cell viability and proliferation rate of the SN56 cholinergic cells or viability of cortical neurons. Co-exposure to radiofrequency exacerbated neurotoxic effect of hydrogen peroxide in SN56 cells, but not in primary cortical neurons, whereas no cooperative effects of radiofrequency exposure with glutamate and 25-35AA beta amyloid were found.
These findings suggest that only under particular circumstances exposure to GSM modulated, 900 MHz signal act as a co-stressor for oxidative damage of neural cells.
このウェブサイトはクッキー(Cookies)を使って、最善のブラウジングエクスペリエンスを提供しています。あなたがこのウェブサイトを継続して使用することで、私たちがクッキーを使用することを許可することになります。