研究のタイプ: 医学／生物学の研究 (experimental study)

[低周波数磁界がヒト被験者の脳の電気活性に与える影響] med./bio.

Effect of low-frequency magnetic fields on brain electrical activity in human subjects

著者: Marino AA, Nilsen E, Chesson Jr AL, Frilot C
掲載誌: Clin Neurophysiol 2004; 115 (5): 1195-1201
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この研究は、正常なヒトの低強度、低周波磁界（MF）への反応を、脳電図（EEG）の非線形定量分析を用いて調べた。8人の被験者は、MF（1 G、60 Hz）の2秒間ばく露、その後の5秒間の無ばく露で構成される一連の試行を受けた。試行中記録されたEEGを位相空間法で分析して、被験者がMFを検出したか否かを評価した。その結果、各被験者において、MFの提示中、脳波に統計的に有意な変化が見られた；この変化は、記録されたEEG信号の決定論的構造の2つの尺度(決定率および再帰率)の増加として現れ、これがMFの感知を示すと解釈した；被験者における反応率は100％であった、と報告している。

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研究目的（著者による）

The effects of exposure of subjects to a 60 Hz magnetic field on the EEG should be investigated to prove the hypothesis that the human brain can detect extremely low frequency magnetic fields.

詳細情報

8 healthy subjects took part in the study, which consisted of an experimental and a positive control part. The experimental part was comprised of a minimum of 60 trials. Each trial consisted of a 2 seconds exposure period and a subsequent 5 seconds non-exposure period. The last 2 seconds (seconds 4 and 5) of these 5 seconds were defined and recorded as the control period and the 2 seconds before (seconds 2 and 3) as the sham exposure period.
A second set of identical trials was carried out as a positive control, where visible light was used as a stimulus during the 2 seconds exposure period.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 60 Hz
ばく露時間: intermittent (2 s on/5 s off) for at least 60 times

ばく露1

主たる特性
周波数 60 Hz
タイプ
  • magnetic field
波形
  • unspecified
ばく露時間 intermittent (2 s on/5 s off) for at least 60 times
ばく露装置
ばく露の発生源／構造
ばく露装置の詳細 pair of coaxial coils, each 130 cm in diameter and consisting of 250 turns of copper wire; the coils were 65 cm apart (the Helmholtz condition) by means of a wooden frame; the subjects sat on a comfortable plastic chair in a dark room with their eyes closed; their sagittal plane was perpendicular to the MF produced by the coils; MF was uniform within 5% in the region of the head and upper chest and within 20% over the thorax and pelvis
Sham exposure A sham exposure was conducted.
Additional information the magnetic field was not accompanied by any visual or auditory cues to the subjects, and consequently the subjects were unaware of the precise times when it was applied
パラメータ
測定量 値 種別 Method Mass 備考
磁束密度 100 µT - 測定値 - -
Additional parameter details

average 60 Hz background magnetic field at the location of the subject was 10 nT, the average geomagnetic field at the location of the subject was 43.2 µT, the geomagnetic component along the direction of the 60 Hz field was 15.6 µT

Reference articles

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露前
  • ばく露中
  • ばく露後

研究の主なアウトカム（著者による）

In all subjects, significant differences were detected in the EEG during the exposure periods compared to the control period. No significant differences were detected between sham exposure periods and control period.
The authors conclude that exposure of subjects to a 60 Hz magnetic field might cause changes in the EEG, and thus the human brain might detect extremely low frequency magnetic fields

研究の種別:

研究助成

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