研究のタイプ: 医学／生物学の研究 (experimental study)

[発達中のひよこ胚に対する長期間の低強度428 MHz無線周波放射の致死的および催奇形性的な影響] med./bio.

Lethal and teratogenic effects of long-term low-intensity radio frequency radiation at 428 MHz on developing chick embryo

著者: Saito K, Suzuki K, Motoyoshi S
掲載誌: Teratology 1991; 43 (6): 609-614
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この研究は、発達中のニワトリ胚に428MHz高周波（RF）電磁界（5.5mW / cm 2）を20日間以上ばく露し、肺への影響を調べた。その結果、胚の死亡および/または催奇形性影響、および孵化の遅延が見られた；これらの影響は、RF電磁界の熱作用によるものではなかった、と報告している。

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研究目的（著者による）

This in vivo study was performed to investigate possible lethal and/or teratogenic effects of athermal low-dose radio frequency exposure on chicken embryos.

詳細情報

In total, 50 fertilized eggs were used in the radio frequency irradiation group and 19 eggs in the control group. Chicks were evaluated up to 30 days after hatching.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 428 MHz
Modulation type: CW
ばく露時間: continuous during incubation for more than 20 days
  • 電力密度: 5.5 mW/cm² (theoretical value)
  • SAR: 3.1 mW/kg minimum (whole body) (3.1-47.1 mW/kg)
  • SAR: 47.1 mW/kg maximum (whole body)

ばく露1

主たる特性
周波数 428 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous during incubation for more than 20 days
Modulation
Modulation type CW
ばく露装置
ばく露の発生源／構造
  • crystal oscillator
チャンバの詳細 eggs incubated and exposed in an incubator at 37 ± 0.5°C and 80% humidity ; they were automatically turned every hour
ばく露装置の詳細 eggs placed on a wooden rack positioned between two parallel aluminum plate electrodes of 34 x 36 cm that were 14 cm apart; their long axis parallel to the electric field
Sham exposure A sham exposure was conducted.
パラメータ
測定量 値 種別 Method Mass 備考
電力密度 5.5 mW/cm² - 計算値 - theoretical value
SAR 3.1 mW/kg minimum 計算値 whole body 3.1-47.1 mW/kg
SAR 47.1 mW/kg maximum 計算値 whole body -
測定および計算の詳細

SAR calculated according to the method of Fujiwara and Amemiya [1982] with the assumption of an ellipsoidal body of 6 x 4.5 cm

Reference articles

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
調査の時期:
  • ばく露後

研究の主なアウトカム（著者による）

Hatchability was observed in 84% of the control group and in 38% of the radio frequency exposed eggs. Almost one fourth of dead embryos in the radio frequency group occured within 10 days after incubation and the rest was due to death within the eggshell following inability to hatch. The severest effect was seen in egg positions where the specific absorption rate was relatively low (4.7-8.6 mW/kg).
A functional abnormality consisting of creeping movement and inability to stand was found in 89% of exposed embryos, but not in the control group.

研究の種別:

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