研究のタイプ: 医学/生物学の研究 (experimental study)

[精子の品質に対する携帯電話電磁界直接照射の影響] med./bio.

The influence of direct mobile phone radiation on sperm quality

掲載誌: Cent European J Urol 2014; 67 (1): 65-71

この研究は、健康被験者から採取した正常な精子に、インビトロ携帯電話電磁放射ばく露を与え、DNA断片化と運動性パラメータへの影響を調べた。正常な精液パラメータを持つ32人の健康な男性から得た精子サンプルをそれぞれ2つに等分し、対照群ばく露群とした。対照群(n = 32)は、恒温槽で5時間保管された。ばく露群(n = 32)は、同様の別の恒温槽で5時間保管されたが、この恒温槽内にはスタンバイ/トークモード携帯電話が置かれた。5時間のインキュベーション後、両群の精子運動パラメータを評価した。また、精子クロマチン分散化試験によるDNA断片化の評価をインキュベーション中の1時間毎に行った。その結果、ばく露群の前進運動精子の数が対照群に比べ有意に少なかった;ばく露群の非前進運動精子の数が対照群に比べ有意に多かった;DNA断片化もばく露群で有意に高かった、と報告している。

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研究目的(著者による)

The effects of an acute in vitro exposure to a 900/1800 MHz GSM electromagnetic field on human sperms should be investigated.

詳細情報

32 healthy men with normal sperm parameters donated a sperm sample, respectively. First, each sample was incubated for 1 hour without exposure and subsequently the test parameters were measured for the first time. Subsequently, the samples were divided equally into two portions, A and B. Portions A of all participants were used as control, portions B were exposed.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900–1,800 MHz
Modulation type: pulsed
ばく露時間: intermittent every 10 minutes for 5 hours (standby mode with outgoing calls every 10 minutes)
-

ばく露1

主たる特性
周波数 900–1,800 MHz
タイプ
  • electromagnetic field
ばく露時間 intermittent every 10 minutes for 5 hours (standby mode with outgoing calls every 10 minutes)
Modulation
Modulation type pulsed
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
Distance between exposed object and exposure source 5 cm
チャンバの詳細 exposure and control samples were placed in two separate incubators (temperature at 27 °C)
ばく露装置の詳細 exposure incubator was equipped with mobile phone as exposure source; mobile phone was placed 5 cm away from the samples and was turned on
Sham exposure A sham exposure was conducted.
パラメータ

No parameters are specified for this exposure.

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
調査の時期:
  • ばく露前
  • ばく露中
  • ばく露後

研究の主なアウトカム(著者による)

DNA fragmentation and non-progressive motility were significantly increased, whereas progressive motility was significantly reduced in exposed sperm samples compared to control.
The authors conclude that an acute in vitro exposure of human sperms to a 900/1800 MHz GSM electromagnetic field influences sperm motility and DNA fragmentation and that further long-term investigations are needed to evaluate possible consequences for male fertility.

研究の種別:

研究助成

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