この研究は、4週齢ラットの歯状回の顆粒細胞の数に対する電磁界(EMF)の出生前ばく露の影響を調べた。ばく露群、擬似ばく露群はそれぞれ3匹の妊娠ラットとした結果、それぞれが孕んでいた6匹の胎仔、5匹の胎仔となった。ばく露群の胎仔は、妊娠の初日から最終日までの間、1日60分間、900MHzのEMFばく露を受けた。新生仔が4週齢になったときに屠殺し、歯状回組織を光学的細胞分画法で分析した。その結果、出生前のばく露群では、顆粒細胞の数の減少が見られた、と報告している。
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To investigate the effects of prenatal exposure to electromagnetic fields on the number of granule cells in the dentate gyrus of rats.
The production and plasticity of new neurons in the dentate gyrus may have an important role in hippocampal functions. Although the production of dentate gyrus granule cells begins prenatally, they are formed at a high rate during the first 20 days after birth. Pregnant rats (n=6) were assigned to a control group and a 900 MHz exposure group. The 4-weeks-old offspring of the control group (n=5) and the exposure group (n=6) was investigated.
周波数 | 900 MHz |
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タイプ |
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ばく露時間 | 60 min/day, from the first to the last day of gestation |
Modulation type | CW |
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ばく露の発生源/構造 | |
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Distance between exposed object and exposure source | 1 cm |
ばく露装置の詳細 | 12 cm long plastic tube cage with a diameter of 5.5 cm, antenna inside the cage |
Prenatal electromagnetic field exposure caused a decrease in the number of granule cells in the dentate gyrus of the rats compared to the control group. In the exposure group morphology was affected (increased number of granule cells with darkly stained neurons), whereas in the control group the morphology of the granule cells was normal. Both groups showed no significant difference in weight.
The results suggest that prenatal exposure to a 900 MHz electromagnetic field affects the development of the dentate gyrus granule cells in the rat hippocampus.
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