この研究は、ヒトの脳電図(EEG)に対する弱い(±200 μT(ピーク値))、超低周波パルス磁界(ELF MF)の影響を調べた。著者らは以前に、パルスELF MFへのばく露が脳電図、特に後頭・頭頂領域のアルファ波(8〜13 Hz)に影響を与える可能性を報告している。今回の実験はこの知見を検証するために、被験者(n = 32)は、提示頻度が異なるパルスMFシーケンス(シーケンス1および2、以前の研究で用いられたものと同じ)ばく露を受け、ばく露前、ばく露中、ばく露後のEEGを測定した。その結果、擬似ばく露の場合と比較して、シーケンス1へのばく露中のEEGの後頭-頭頂領域でのアルファ波活動は低下した;その一方、シーケンス2ばく露後において、同じ領域でのアルファ波活動は高かった;このような影響は、パルスMFばく露の約5分後に生じた;このような知見は、先行研究での観察を支持すると、報告している。
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To examine the effects of pulsed extremely low frequency magnetic field sequences upon alpha wave activity (8-13 Hz) of the human EEG over the occipital-parietal regions.
Two previous studies (see publication 11906 and publication 10628) determined that exposure to pulsed extremely low frequency electromagnetic fields can affect the EEG, notably the alpha wave frequency (8-13 Hz). In the present study 22 participants from two previous studies (see publication 11906 [sequence 2 with a refractory period of 5000 ms] and publication 10628 [sequence 1 with a refractory period of 1200 ms]) and 10 additional subjects were randomly assigned to two different pulsed magnetic field sequences, used in the previous studies. Participation consisted of two sessions (exposure and sham exposure), separated by approximately 1 week (7+/-2 days).
ばく露 | パラメータ |
---|---|
ばく露1:
0–500 Hz
Modulation type:
pulsed
ばく露時間:
continuous for 15 min
|
|
two different pulse forms were used a) pulses with a refractory period of 1200 ms b) pulses with a refractory period of 5000 ms
周波数 | 0–500 Hz |
---|---|
タイプ |
|
ばく露時間 | continuous for 15 min |
Modulation type | pulsed |
---|---|
Pulse width | 853 ms |
Rise time | 1 ms |
ばく露の発生源/構造 | |
---|---|
ばく露装置の詳細 | three orthogonal square Helmholtz coils with 2.0 m, 1.75 m, 1.5 m sides and 10 turns of 8-gauge stranded conductor each |
Sham exposure | A sham exposure was conducted. |
測定量 | 値 | 種別 | Method | Mass | 備考 |
---|---|---|---|---|---|
磁束密度 | 200 µT | peak | 測定値 | - | - |
Compared to sham exposure, alpha wave activity was lowered over the occipital-parietal regions of the brain during exposure to sequence 1, while alpha wave activity over the same regions was higher after sequence 2 exposure. The effects occured after 5 min of exposure and were dependent on the order of exposure (magnetic field followed by sham exposure).
This study supports previous observations of EEG changes after 5 min pulsed extremely low frequency magnetic field exposure. The results also suggest that a previous exposure to the pulsed magnetic field sequence determined subjects´ responses in the present experiment, i.e. subjects previously exposed to sequence 1(and now to sequence 2) displayed higher occipital alpha wave activity after magnetic field exposure. Subjects previously exposed to sequence 2 (and now sequence 1) displayed lower alpha wave activity over posterior scalp regions in the present study.
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