研究のタイプ: 医学/生物学の研究 (experimental study)

[無線周波電磁界の影響下での睡眠中の心臓自律活動] med./bio.

Cardiac Autonomic Activity during Sleep under the Influence of Radiofrequency Electromagnetic Fields

掲載誌: Somnologie (Somnology) 2005; 9 (4): 180-184

この研究は、健康な若い男性を対象に、睡眠中の心拍変動(HRV)に対するデジタル携帯電話高周波電磁界の影響を調べた。睡眠実験室において、被験者はそれぞれ、電磁界ばく露および擬似ばく露の条件下で2回の睡眠ポリグラフ検査を受けた。電磁界レベルは低いため、熱的影響は排除されたと想定した。HRVを、時間領域および周波数領域の両方で心電図から評価した。その結果、ほとんどのHRVパラメータについて、睡眠段階間の有意差が見られた;特に、RR間隔のスペクトル分析に基づけば、徐波睡眠は、低いLF / HF比(HRVの低周波数成分と高周波数成分の比)で特徴付けられ、心臓自律神経系制御での交感神経に対する副交感神経活動の優位性が示された;REM睡眠中、このバランスは交感神経緊張に有利な方へシフトした;すべてのHRVパラメータについて、電磁界ばく露擬似ばく露の間に有意差は見られなかった、と報告している。

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研究目的(著者による)

To study the influence of radiofrequency electromagnetic fields emitted by digital mobile telephones on heart rate variability during sleep in healthy young men.

詳細情報

Field intensity was weak so that thermal effects could be excluded.
The relation between low frequency and high frequency components of heart rate variability represents the balance between the two branches of the autonomic nervous system. The high frequency component reflecting sinus arrhythmia, has been attributed to the modulation of the parasympathetic output. The low frequency component has been referred to both sympathetic and parasympathetic activity.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 8 h

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 8 h
Modulation
Modulation type pulsed
Pulse width 577 µs
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源/構造
  • セルラ-電話
Distance between exposed object and exposure source 40 cm
チャンバの詳細 Soundproof and electrically shielded sleep laboratory
ばく露装置の詳細 The mobile phone was positioned at the head of the bed at a distance of 40 cm to the vertex of the subject with the antenna axis perpendicular to the axis of the subject's body.
Sham exposure A sham exposure was conducted.
Additional information Following an adaptation night, two polysomnographies were carried out for each subject over 8 h from 23:00 h to 7:00 h with or without exposure to the EMF in randomized and single-blind order. Field intensity was weak so that thermal effects could be excluded.
パラメータ
測定量 種別 Method Mass 備考
電力 8 W peak - - -
電力密度 0.05 mW/cm² mean - - at 40 cm

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露中

研究の主なアウトカム(著者による)

Under these experimental conditions, no influence of weak radiofrequency electromagnetic fields on cardiac autonomic activity could be proven.
For most parameters of heart rate variability, significant differences between sleep stages were revealed. Particularly, on the basis of spectral analysis of the RR intervals, slow wave sleep was characterized by a low LF/HF ratio of the low frequency and high frequency components of heart rate variability, indicating a predominance of the parasympathetic over the sympathetic activity in autonomic cardiac control. During REM sleep, the balance was shifted in favour of the sympathetic tone. For all heart rate parameters, no significant differences were revealed between electromagnetic field exposure and sham exposure.

研究の種別:

研究助成

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