研究のタイプ: 医学/生物学の研究 (experimental study)

Ultrawide-band electromagnetic pulses induced hypotension in rats. med./bio.

掲載誌: Physiol Behav 1998; 65 (4-5): 753-761

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研究目的(著者による)

Functional indices of the cardiovascular system (heart rate, systolic, mean, and diastolic pressures) were selected to represent biological endpoints that may be susceptible to the ultrawide-band radiation.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 0.09–2.78 GHz
Modulation type: pulsed
ばく露時間: continuous for 6 min
ばく露2: 0.1–2.5 GHz
Modulation type: pulsed
ばく露時間: continuous for 6 min

ばく露1

主たる特性
周波数 0.09–2.78 GHz
タイプ
  • electromagnetic field
波形
  • pulsed
特性
  • guided field
ばく露時間 continuous for 6 min
Additional information medium frequency 0.5 GHz, fractional bandwidth 187%, estimated according to Foster, P. R.: Antennas and UWB signals. In: Taylor, J. D., ed. Introduction to ultra-wideband radar systems. Boca Raton, FL: CRC Press; 1995:237-248.
Modulation
Modulation type pulsed
Pulse width 1 ns
Rise time 180 ps
Repetition frequency 500 Hz
ばく露装置
ばく露の発生源/構造
  • GTEMセル
  • spark gap pulse generator
Distance between exposed object and exposure source 72.7 cm
チャンバの詳細 The tapered parallel plate GTEM cell (a flared rectangular coaxial transmission line) was 190 cm long and 92 cm high at the end. The lower compartment was 38.5 cm wide and 16.5 cm high at the rat's location.
ばく露装置の詳細 Rats were placed in an exposure holder made from an acrylic tube (6.5 cm i.d., 3.2 mm wall thickness, 28 cm length) with ventilation slots and polyethylene endcaps. The major axis of the animal was placed in parallel with the magnetic vector at 72.7 cm from the source end of the GTEM cell. The animal was isolated from the ground plane by placing the exposure holder on an acrylic stand of 4.2 cm height.
Sham exposure A sham exposure was conducted.
Additional information During sham exposure, all UWB conditions were maintained except for the trigger pulses to cause the spark.
パラメータ
測定量 種別 Method Mass 備考
電界強度 93 kV/m peak 測定値 - ± 5 kV/m
電力密度 1.15 mW/cm² mean 指定なし - -
SAR 70 mW/kg average over mass 指定なし whole body -

ばく露2

主たる特性
周波数 0.1–2.5 GHz
タイプ
  • electromagnetic field
波形
  • pulsed
特性
  • guided field
ばく露時間 continuous for 6 min
Additional information medium frequency 0.49 GHz, fractional bandwidth 185%
Modulation
Modulation type pulsed
Pulse width 1.03 ns
Rise time 200 ps
Repetition frequency 1,000 Hz
ばく露装置
ばく露の発生源/構造
  • E1と同じ装置
パラメータ
測定量 種別 Method Mass 備考
電界強度 84.6 kV/m peak 測定値 - ± 4 kV/m
電力密度 1.96 mW/cm² mean 指定なし - -
SAR 121 mW/kg average over mass 指定なし whole body -

ばく露を受けた生物:

方法 影響評価項目/測定パラメータ/方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム(著者による)

Significant decrease in arterial blood pressure (hypotension) was found. In contrast, heart rate was not altered by these exposures. The ultrawide-band radiation-induced hypotension was a robust, consistent, and persistent effect.

研究の種別:

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