この研究は、焦点てんかん患者(n=12)の脳電図(EEG)上の棘波(スパイク)活動に対するGSM様信号の影響を、二重ブラインド化、交差化、カウンターバランス化した実験デザインで調べた。ばく露(真または擬似)セッション(45分間)およびばく露後セッション中のEEGを記録した。その結果、擬似ばく露下に比べ、真のばく露下で、スパイク活動は低くなる傾向を示した;EEGスペクトル分析で、真のばく露下でガンマ帯の有意な増加が示唆された;脳領域間関連解析で、ベータ帯での半球間の瞬間的コヒーレンスがばく露中に増加することが示唆された;しかし、携帯電話使用によるてんかん発作のリスク上昇を示す兆候は見られなかった、と報告している。
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The hypothesis should be tested that an acute exposure of epileptic patients to a 902.4 MHz electromagnetic field from a mobile phone might influence the EEG spiking rate.
Preceding studies indicated an increased cortical excitability and inter-hemispheric connectivity caused radiofrequency exposure, which led to the hypothesis of this study. In 12 volunteers with focal epilepsy and lateralized hemispheric spiking, an EEG was recorded both under real and sham exposure conditions separated by 1 week.
周波数 | 902.4 MHz |
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タイプ |
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ばく露時間 | continuous for 45 min |
Modulation type | pulsed |
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Repetition frequency | 217 Hz |
Additional information |
the signal was additionally pulsed with a frequency of 8.33 Hz |
ばく露の発生源/構造 |
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Distance between exposed object and exposure source | 1.5 cm |
ばく露装置の詳細 | a mobile phone was positioned on the left and on the right side of the head, respectively, with the help of a modified helmet; during exposure, the active phone was localized on the side of the head where the patient had the epileptic focus and the other one was deactivated |
Sham exposure | A sham exposure was conducted. |
Neither the spiking rate nor the risk of incoming seizures was significantly different between expoure and sham exposure, i.e. the clinical status of the patients was not influenced. However, a significant increase of gamma wave spectral power and of inter-hemispheric coherence for beta wave rhythms was found in exposed patients compared to sham exposure.
The authors conclude that the results do not indicate any negative effects of an acute exposure of epileptic patients to a 902.4 MHz electromagnetic field from a mobile phone.
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