この研究は、無線周波電磁界（GSM携帯電話電磁界）の事前ばく露により、大腸菌への抵抗性が変化するか否かを、ラットで実験した。（適応応答の）チャレンジドースの大腸菌を投与した時のマウスの生存率は、無線周波数電磁界事前ばく露群は56％、事前ばく露なしの群では20%であった、と報告している。
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The effects of pre-exposure of mice to a radio frequency electromagnetic field on the survival rate after a bacterial infection should be investigated.
Remark EMF-Portal: This article presents the same data as a previous article (Mortazavi et al. 2012).
110 mice were divided into the following groups: 1) 2 h/day exposure to electromagnetic field and injection of Escherichia coli bacteria (n=10), 2) 2 h/day exposure and sham injection (saline solution) (n=5), 3) sham exposure and bacteria injection (n=5), 4) 4 h/day exposure and bacteria injection (n=10), 5) exposure and sham injection (n=5), 6) sham exposure and bacteria injection (n=5), 7) 8 h/day exposure and bacteria injection (n=10), 8) 8 h/day exposure and sham injection (n=5), 9) sham exposure and bacteria injection (n=5), 10) 12 h/day exposure and bacteria injection (n=10), 11) 12 h/day exposure and sham injection (n=5), 12) sham exposure and bacteria injection (n=5), 13) replication of group 10 (n=15), 14) replication of group 12 (n=15).
background radiation was 0.1 µSv/h
| ばく露の発生源／構造 |
|
|---|---|
| Distance between exposed object and exposure source | 5 cm |
| ばく露装置の詳細 | cell phone was used in talk mode during exposure; mice were immobilized by placing their bodies in plastic restrainers; restrainers were placed around the antenna in a circular position |
| Sham exposure | A sham exposure was conducted. |
| 測定量 | 値 | 種別 | Method | Mass | 備考 |
|---|---|---|---|---|---|
| SAR | 1.4 W/kg | - | - | - | - |
The results of the groups with sham injection of bacteria (2, 5, 8 and 11) were not presented or discussed.
Group 4 (4 h/day) showed no significantly different result in comparison to its corresponding sham exposure group (6) according to the authors, even though the associated p value of 0.046 would actually represent a significantly lower survival rate. (Remark EMF-Portal: However, as this value was relatively high, the authors spoke of a "borderline" p value, which they did not take into account.)
Group 13 (12 h/day) showed a significantly higher survival rate compared to its corresponding sham exposure group (14), as did the pooled results of groups 13 and 10 in comparison to the pooled results of groups 14 and 12.
The authors conclude that pre-exposure of mice to a radio frequency electromagnetic field might increase the survival rate after a bacterial infection. This could be the result of an adaptive response and activation of the immune system, what might be of potential therapeutic use.
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