研究のタイプ: 医学／生物学の研究 (experimental study)

[900 MHz携帯電話が放射する電磁界への全身ばく露はアポトーシス抑制性bcl-2のタンパクレベルに影響を与えないようである] med./bio.

Whole-body exposure of radiation emitted from 900 MHz mobile phones does not seem to affect the levels of anti-apoptotic bcl-2 protein

著者: Yilmaz F, Dasdag S, Akdag Z, Kilinc N
掲載誌: Electromagn Biol Med 2008; 27 (1): 65-72
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この研究は、900MHz携帯電話電磁界に全身ばく露したラットの脳内のアポトーシス抑制性遺伝子bcl-2のタンパクレベルを調べた。8匹のSDラットをばく露群、擬似ばく露群に分けた。ばく露には携帯電話の通話モードを用い、1日20分間、1ヶ月間行った。擬似ばく露群は携帯電話の電源をオフにして、同じ処理を行った。免疫化学的染色でbcl-2を測定した。その結果、ばく露群の脳内のbcl-2のタンパクレベルに変化は見られなかった、と報告している。

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研究目的（著者による）

To investigate the anti-apoptotic bcl-2 protein in rat brain and testes after whole body exposure to irradiation emitted from 900 MHz cellular phones.

詳細情報

16 male rats were separated into a control and an experimental group. For the experimental group the phones transmitted speech for 20 minutes per day for one month.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: repeated daily exposure, 20 min/day, for 1 month

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
ばく露時間 repeated daily exposure, 20 min/day, for 1 month
Modulation
Modulation type pulsed
Additional information

The mobile phones transmitted human speech from a tape to the base station.
ばく露装置
ばく露の発生源／構造
  • セルラ－電話
  • GSM
Distance between exposed object and exposure source 5 mm
チャンバの詳細 The rats were confined in Plexiglas cages (20 cm x 10.5 cm x 10 cm) with ventilation holes, and the mobile phones were placed under the cages.
ばく露装置の詳細 Exposure began when the rats settled down to a prone position and selected a fixed location inside the cage spontaneously.
Sham exposure A sham exposure was conducted.
Additional information The same phones were placed under the control rats but they were turned off.
パラメータ
測定量 値 種別 Method Mass 備考
電力 2 W peak - - -
電力 250 mW mean - - -
電界強度 13.59 V/m mean 測定値 - -
電力密度 0.047 mW/cm² mean 測定値 - -
SAR 3.13 W/kg effective value 計算値 1 g -
SAR 0.52 W/kg effective value 測定値および計算値 whole body 0.29- 0.87 W/kg
Additional parameter details

Taking into account the very simple shape of the model used in the simulation, the SAR values are approximate. In addition, due to the adaptive power control of the base station, the radiated power was variable during the study. Minimum and maximum SAR levels were also measured.

測定および計算の詳細

Average field strength and power density were measured using a radiation meter. For checking the availability of the signal, cell sensor equipment was used having a sensitivity of 0-10 mW/cm². The FDTD method was used to calculate SAR. The simulation was performed using Finite Integration Technique (FIT) which in the time domain case is similar to FDTD. The FCC recommended parameters for average muscle dielectric constant and conductivity at 900 MHz were used to simulate the rat model which was an ellipsoid with 100 and 28 mm semi axis. The phone model was a metallic box of 90 x 40 x 15 mm mounted with a monopole antenna of 80 mm. Distance between the rat model and the phone model was 5 mm.

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム（著者による）

The results showed that 20 minutes of the irradiation emitted from 900 MHz cellular phones did not alter anti-apoptotic bcl-2 protein in the brain and testes of rats.
It was concluded that bcl-2 may not be involved in the effects of irradiation on the brain and testes of rats.

研究の種別:

研究助成

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