研究のタイプ: 医学／生物学の研究 (experimental study, review/survey)

[DNA、タンパク質、DNA-タンパク質複合体に対する無線周波電磁界の影響] med./bio.

[Effects of radiofrequency electromagnetic fields on DNA, proteins, and DNA-protein-complexes]

著者: Hansen V, Rüger W
掲載誌: Edition Wissenschaft 1996; 8: 3-38
Journal not peer-reviewed
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この論文は、社団法人die Forschungsgemeinschaft Funk （1992年から活動している研究資金提供団体）へのドイツ語の研究報告書である。２部構成であり、パート1は、原核生物を用いた実験を設計し、電磁界の生物学的影響を評価した。原核生物は、物理的または化学的因子による生物学的損傷を追跡するのに役立つ。その結果、3か月の合計ばく露時間でバクテリオファージの生存率を調べたが、対照群に比べ、生存率の低下は見られないなどの結果から、この微生物のDNAも感受性タンパク質も電磁界による損傷を受けないという結論が導かれると報告している。パート2は、生物試料の変調無線周波放射ばく露試験に用いられるばく露システムの詳細な技術データ、並びに測定された反射および透過係数が示されている。再現性のある、実質的に均一な培地のばく露の達成を検証するために、広範な数値計算も実行された、と報告している。

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研究目的(acc. to editor)

To study the effects of radiofrequency electromagnetic fields on biological material (DNA, protein, DNA-protein complexes, virus, bacterium). The study consists of a database investigation, a numerical calculation of the distribution of the field in the samples, and an experimental investigation. Here, only the experimental investigation is presented.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for about 100 days or about 30 days
  • 電力: 8 W mean (set power level during the burst; the mean power being approx. 25 - 35% below 1 W (e.g. 0.67 W))
  • 電界強度: 729 V/m mean (during the burst and in the boresight of the waveguide)
  • SAR: 47 mW/kg mean (during the burst; the mean SAR being 6 mW/kg)
ばく露2: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for 1 week
ばく露3: 1,750 MHz
Modulation type: pulsed
ばく露時間: continuous for 1 week
  • 電力: 1 W mean (set power level during the burst; the mean power being approx. 25 - 35% below 125 mW (e.g. 97 mW))
  • 電界強度: 484.5 V/m mean (during the burst and in the boresight of the waveguide)
  • SAR: 87 mW/kg mean (during the burst; the mean SAR being 11 mW/kg)
ばく露4: 900 MHz
Modulation type: pulsed
ばく露時間: continuous for approx. 3 min or up to 12 min depending on the sample
ばく露5: 1,750 MHz
Modulation type: pulsed
ばく露時間: continuous for approx. 3 min or up to 12 min depending on the sample
ばく露6: 900–1,750 MHz
Modulation type: pulsed
ばく露時間: continuous for approx. 3 minutes
  • 電力: 8 W mean (power during the burst was varied from 33 dBm via 36 dBm to 39 dBm equivalent to approx. 8 W)

General information

This article not only describes several biological experiments (part 1) but also the creation and thorough analysis of the RF exposure system as well as calculations of electric field strengths and SAR values (part 2). All exposure parameter values given are valid during the burst.

ばく露1

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 continuous for about 100 days or about 30 days
Modulation
Modulation type pulsed
Duty cycle 12.5 %
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源／構造
  • GSM mobile phone feeding an R9 waveguide measuring cell of 247.65 mm x 123.80 mm x 900 mm
ばく露装置の詳細 Up to 30 glass ampoules in three lines containing 0.1 ml (or 1 ml?) of the culture medium were positioned inside the waveguide.
パラメータ
測定量 値 種別 Method Mass 備考
電力 8 W mean 測定値 - set power level during the burst; the mean power being approx. 25 - 35% below 1 W (e.g. 0.67 W)
電界強度 729 V/m mean 計算値 - during the burst and in the boresight of the waveguide
SAR 47 mW/kg mean 計算値 - during the burst; the mean SAR being 6 mW/kg
Additional parameter details

The SAR value given is valid for an array of 30 glass ampoules containing 0.1 ml of the culture medium.

ばく露2

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 continuous for 1 week
Modulation
Modulation type pulsed
Duty cycle 42.2 %
Repetition frequency 730.2 Hz
Additional information

Pulse repetiton rates of 2/ 8.3/ 217/ 730.2 Hz with duty factors of 1:867/ 1:209/ 1:8/ 1:2.37 were used.
ばく露装置
ばく露の発生源／構造
  • signal generator feeding an R9 waveguide measuring cell of 247.65 mm x 123.80 mm x 900 mm
ばく露装置の詳細 Up to 30 glass ampoules in three lines containing 0.1 ml (or 1 ml?) of the culture medium or petri dishes (8 cm, 25 ml) were positioned inside the waveguide.
パラメータ
測定量 値 種別 Method Mass 備考
電力 8 W mean 測定値 - -
電界強度 729 V/m mean 計算値 - in the boresight of the waveguide
SAR 47 mW/kg mean 計算値 - -
電力 2 W mean 測定値 - -
電界強度 364.5 V/m mean 計算値 - in the boresight of the waveguide
SAR 11.75 mW/kg mean 計算値 - -
Additional parameter details

The SAR values given are valid for an array of 30 glass ampoules containing 0.1 ml of the culture medium.

ばく露3

主たる特性
周波数 1,750 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 continuous for 1 week
Modulation
Modulation type pulsed
Duty cycle 12.5 %
Repetition frequency 217 Hz
ばく露装置
ばく露の発生源／構造
  • DCS 1800 mobile phone feeding an R18 waveguide measuring cell of 129.54 mm x 64.77 mm x 995 mm
ばく露装置の詳細 Up to 20 glass ampoules in two lines containing 0.1 ml (or 1 ml?) of the culture medium or petri dishes (8 cm, 25 ml) were positioned inside the waveguide.
パラメータ
測定量 値 種別 Method Mass 備考
電力 1 W mean 測定値 - set power level during the burst; the mean power being approx. 25 - 35% below 125 mW (e.g. 97 mW)
電界強度 484.5 V/m mean 計算値 - during the burst and in the boresight of the waveguide
SAR 87 mW/kg mean 計算値 - during the burst; the mean SAR being 11 mW/kg
Additional parameter details

The SAR value given is valid for an array of 20 glass ampoules containing 0.1 ml of the culture medium.

ばく露4

主たる特性
周波数 900 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 continuous for approx. 3 min or up to 12 min depending on the sample
Modulation
Modulation type pulsed
Duty cycle 42.2 %
Repetition frequency 730.2 Hz
Additional information

Pulse repetiton rates of 2/ 8.3/ 217/ 730.2 Hz with duty factors of 1:867/ 1:209/ 1:8/ 1:2.37 were used.
ばく露装置
ばく露の発生源／構造
  • signal generator feeding a parallel-plate waveguide measuring cell
ばく露装置の詳細 Quartz cuvettes were enclosed in parallel-plate waveguides and inserted in the sample holder of a photometer.
パラメータ
測定量 値 種別 Method Mass 備考
電力 0.75 W mean 測定値 - -
電界強度 577 V/m mean 推定値 - in the measuring cell

ばく露5

主たる特性
周波数 1,750 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 continuous for approx. 3 min or up to 12 min depending on the sample
Modulation
Modulation type pulsed
Duty cycle 42.2 %
Repetition frequency 730.2 Hz
Additional information

Pulse repetiton rates of 2/ 8.3/ 217/ 730.2 Hz with duty factors of 1:867/ 1:209/ 1:8/ 1:2.37 were used.
ばく露装置
ばく露の発生源／構造
  • same setup as in E4
パラメータ
測定量 値 種別 Method Mass 備考
電力 0.88 W mean 測定値 - -
電界強度 625 V/m mean 推定値 - in the measuring cell

ばく露6

主たる特性
周波数 900–1,750 MHz
タイプ
  • electromagnetic field
特性
  • guided field
ばく露時間 continuous for approx. 3 minutes
Additional information Tests were performed at 900 and 1750 MHz.
Modulation
Modulation type pulsed
Repetition frequency 8.3 Hz
ばく露装置
ばく露の発生源／構造
  • same setup as in E4
パラメータ
測定量 値 種別 Method Mass 備考
電力 8 W mean 測定値 - power during the burst was varied from 33 dBm via 36 dBm to 39 dBm equivalent to approx. 8 W

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
調査の時期:
  • ばく露中
  • ばく露後

研究の主なアウトカム（著者による）

The results revealed no detectable effects in any of the biological systems.

研究の種別:

研究助成

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