著者:
Deshmukh PS, Megha K, Nasare N, Banerjee BD, Ahmed RS, Abegaonkar MP, Tripathi AK, Mediratta PK
掲載誌: Biomed Environ Sci 2016; 29 (12): 858-867
この研究は、フィッシャーラットを用いて、認知機能、脳組織の熱ショックタンパク質(HSP70)レベルおよびDNA損傷に対する低レベル亜慢性のマイクロ波放射(MWR)の影響を調べた。ばく露は90日間、周波数900、1800、2450MHzの3つのばく露群および1つの擬似ばく露対照群を設けた(動物の数は抄録に記載なし)。900MHzばく露群のSARは5.953×10-4W/kg、1800MHzばく露群のSARは5.835×10-4W/kg、2450MHzばく露群のSARは6.672×10-4W/kgである。ばく露終了後に、高架十字迷路試験、モーリス水迷路試験で認知機能を評価し、その後、屠殺して脳組織のHSP70レベルおよびDNA損傷を評価した。その結果、いずれのばく露群においても、認知機能低下、脳組織のHSP70レベルおよびDNA損傷の上昇が見られたと報告している。
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Male rats were divided into 4 groups (n=6 each): 1) exposure to a 900 MHz electromagnetic field, 2) exposure to a 1800 MHz electromagnetic field, 3) exposure to a 2450 MHz electromagnetic field, 4) sham exposure.
Deshmukh et al. (2015) conducted a study using the same design and methods but with a exposure duration of 180 days.
Learning, memory and spatial memory were significantly impaired in the exposure groups (groups 1-3) compared to the sham exposure group (group 4). DNA damage and the Hsp70 protein expression were significantly increased in the exposure groups compared to the sham exposure group. The body temperature showed no differences between before and after exposure in any group.
The authors conclude that exposure of rats to 900-2450 MHz electromagnetic fields might have deleterious effects on the brain.