この研究は、アルビノ雄ラット（n=40）を用い、耳下腺への携帯電話電磁放射にばく露したラットの耳下腺組織の変化を調べ、加えてローズマリー抽出物摂取群における同様の影響も調べた。ラットを対照群、ローズマリー抽出物摂取群、携帯電話ばく露群、ローズマリー抽出物摂取+携帯電話ばく露群の4群（各n=10）に分け、ばく露終了後に耳下腺を摘出しで組織学的検査（光学および電子顕微鏡的観察）、酸化ストレスマーカの測定（マロンジアルデヒド（MDA）、総抗酸化能（TAC））を行った。その結果、携帯電話ばく露群では、光学および電子顕微鏡的レベルの耳下腺組織構造変化が観察された；ローズマリー抽出物摂取+携帯電話ばく露群では、そのような組織像の変化が改善されていた、と報告している。（JEIC注：アブストラクトにはばく露パラメータの記述無し）
The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →
The effects of exposure of rats to a 900 MHz electromagnetic field (GSM) on the histology and oxidative stress of the parotid glands and the protective role of rosemary extract should be investigated.
Rosemary has antioxidative and anti-inflammatory effects. However, its protective role against EMF induced oxidative stress has not been investigated to date.
40 rats were divided into 4 groups (n=10 each): 1) exposure to the electromagnetic field, 2) treatment with rosemary extract, 3) co-exposure to the electromagnetic field and rosemary extract, 4) control group.
220 mg/kg body weight rosemary extract was administered orally daily during the exposure period
| 周波数 | 900 MHz |
|---|---|
| ばく露時間 | 4 hours/day for 30 days |
| Additional information | GSM |
| ばく露の発生源／構造 |
|
|---|---|
| チャンバの詳細 | cage |
| ばく露装置の詳細 | the mobile phone was placed over the cage of the animals, which was surrounded by aluminum foil to focus waves and shield the animals from external fields |
| Additional information | non-EMF-exposed groups were held separately in a different room |
Histological and ultrastructural examinations revealed changes in the EMF exposure group (group 1) compared to the control group (group 4) and rosemary extract group (group 2). In histology, cytoplasmic vacuoles, irregular outlines and darkly stained nuclei were observed in acini. Moreover, mucous release was increased and thick connective tissue septa with congested blood vessels were found.
The electron microscopy confirmed this indication with heterochromatic nuclei and damaged organelles as well as collagen fibers in the basement membrane being found.
In the co-exposure group (group 3), most histological and ultrastructural changes were reverted and exhibited the state of the control group.
The diameter and number of serous acini as well as the parenchyma/stroma ratio were significantly decreased in the EMF exposure group compared to the control group and co-exposure group.
In oxidative stress tests, lipid peroxidation was significantly increased while the total antioxidant capacity was significantly decreased in the exposure group compared to the control group and co-exposure group.
The authors conclude that an exposure of rats to a 900 MHz electromagnetic field (GSM) might alter the histology of the parotid glands possibly due to oxidative stress and that rosemary might play a protective role against this effect through its antioxidant activity.
このウェブサイトはクッキー（Cookies）を使って、最善のブラウジングエクスペリエンスを提供しています。あなたがこのウェブサイトを継続して使用することで、私たちがクッキーを使用することを許可することになります。
