この研究は、ネンブタール(40 mg / kg、腹腔内投与)で麻酔をかけた白ラットを用いて、ミリ波領域の電磁放射へのばく露後の視床下部の視索上核のニューロンからのバックグラウンドスパイク活動を細胞外記録し、その分析を行った。ニューロンの分布は、規則性の程度、ニューラルストリームのダイナミクスの性質、スパイク間隔のヒストグラムのモダリティによって決定した。スパイク間隔の変動係数に加えて、平均ニューロンスパイク周波数を計算した。その結果、バックグラウンドのスパイク活動の変化が示された;主として、記録されたスパイクストリームの内部構造が影響を受けたことが示された;主な変化は、スパイク間の期間およびスパイク活動の規則性の程度に見られた;ニューロン集団の平均スパイク周波数の変化は統計学的に有意であった、と報告している。
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The study describes a comparative analysis of the background spike activity of neurons in the supraoptic nucleus of the hypothalamus after single exposures to low intensity electromagnetic fields at different frequencies, with the aim of assessing the functional state of the central nervous system and identifying a number of features in the action of millimeter wave irradiation on the brain.
Experiments were performed on rats anesthetized with Nembutal (40 mg/kg). Experimental group consisted of 12 rats, control group consisted of 6 rats.
The functional state of the CNS is often assessed by using the background spike activity of neurons. Measurements of spike frequency provide only a partial reflection of the nature of the spike stream, while identification of parameters based on analysis of interspike intervals provides a more informative assessment of spontaneous activity in different physiological processes.
The data show that single sessions of irradiation of animals' heads with low intensity electromagnetic fields in the millimeter wave range were accompanied by insignificant changes in mean spike frequency. Modification of the spike frequency within the normal range and the absence of significant changes provide evidence of the subthreshold (in terms of its biological significance) nature of the actions of low intensity electromagnetic fields on the functioning of the central nervous system, whose responses depend on the initial functional state