To determine if exposure to a radiofrequency electromagnetic field similar to those used in cellular phone has any effects on the growth of a central nervous system tumor. The intracranial 9L (gliosarcoma cells) tumor model was used.
Rats were assigned randomly to one of three exposure groups that were injected in the brain with three different numbers of tumour cells.
Modulation type | cf. additional info |
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Additional info |
Exposure source | |
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Chamber | RF field exposure was carried out in the "chamberettes" described in [Moros et al., 1998]. Each chamberette consisted of four carousels stacked vertically. In order to factor out possible confounders, the angular orientation of the carousel and the location (shelf and chamber) were varied every day according to a randomization schedule. |
Setup | Ten animals, each housed in a cylindrical restrainer, were placed on a carousel, equidistant from the central dipole antenna with their heads pointing towards the center. Sham-exposure carousels had no antenna. Larger restraint devices were used as the animals grew, in order to maintain the appropriate distance from the source. |
Sham exposure | A sham exposure was conducted. |
Additional info | Exposure of the animals started 4 weeks before and continued up to 150 days after the implantation of tumour cells. |
Exposure under these conditions did not result in any differences in the growth of 9L glioma cells implanted in rats. The animals exposed to CDMA (code division multiple access) or FMCW (frequency modulated continuous wave) had similar survival parameters. Survival curves for the exposed groups showed no significant differences compared to sham-exposed controls.
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