この研究は、MRI装置からの静磁界、低周波磁界、無線周波(RF)電磁界のそれぞれ単独ばく露、および3つのタイプの組み合わせばく露を、Sprague-Dawleyラットに与え、ばく露後の血液脳関門のエバンスブルー透過生を調べた。その次に、915 MHzマイクロ波(連続波および種々の低周波(8-215 Hz)での変調波)ばく露をFischer 344に与え、ばく露中の内因性アルブミンおよびフィブリノーゲン漏出を調べた。その結果、RF電磁界ばく露には、血液脳関門の透過生を高める影響が見られた;この影響は、RF連続波で見られたが、パルス化RF放射においてより大きかった、と報告している。
The detailed summary of this article is not available in your language or incomplete. Would you like to see a complete translation of the summary? Then please contact us →
First: To study the dye permeability (Evans blue) of the blood-brain barrier after exposure to components of the MRI electromagnetic fields. Static magnetic fields, low frequency magnetic fields, radiofrequency electromagnetic fields (RF), and a combination of these three types of fields were applied to Sprague-Dawley rats in these experiments.
Second: To study the leakage of endogenous albumin and fibrinogen during exposure to microwaves of 915 MHz (CW and modulated at various low frequencies (8-215 Hz)). In these experiments Fischer 344 rats were used.
ばく露 | パラメータ |
---|---|
ばく露1:
ばく露時間:
continuous for 2 h
|
- |
ばく露2:
Modulation type:
pulsed
ばく露時間:
continuous for 2 h
|
|
ばく露3:
Modulation type:
pulsed
ばく露時間:
continuous for 2 h
|
|
ばく露4:
915 MHz
Modulation type:
CW
|
|
ばく露5:
915 MHz
Modulation type:
pulsed
|
|
ばく露6:
ばく露時間:
continuous for 1 h
|
|
Modulation type | pulsed |
---|---|
Repetition frequency | 1 Hz |
Additional information |
pulse width of 400 to 800 ms |
ばく露の発生源/構造 |
|
---|
測定量 | 値 | 種別 | Method | Mass | 備考 |
---|---|---|---|---|---|
電力 | 0.2 W | - | - | - | - |
Modulation type | pulsed |
---|---|
Repetition frequency | 1 Hz |
Additional information |
pulse width of 400 to 800 ms |
ばく露の発生源/構造 |
|
---|
周波数 | 915 MHz |
---|---|
タイプ |
|
特性 |
|
Modulation type | pulsed |
---|---|
Additional information |
pulse rates of 8, 16, 50, and 215 Hz pulse widths of 0.6 to 4 ms |
ばく露の発生源/構造 | |
---|---|
Additional information | Rats were not anaesthetized during the exposure. |
測定量 | 値 | 種別 | Method | Mass | 備考 |
---|---|---|---|---|---|
電力 | 10 W | peak | - | - | 1-10 W/pulse |
The conclusion is that radiofrequency radiation has a increasing effect on the permeability of the blood-brain barrier. The effect was found for CW radiation and more pronounced for pulsed RF radiation. The effect of MRI high field exposure could not be confirmed.
このウェブサイトはクッキー(Cookies)を使って、最善のブラウジングエクスペリエンスを提供しています。あなたがこのウェブサイトを継続して使用することで、私たちがクッキーを使用することを許可することになります。