研究のタイプ: 医学／生物学の研究 (observational study)

[電磁界を原因と思う特発性環境不耐性（IEI-EMF）の個人の睡眠障害：生物学的マーカであるメラトニンの評価] med./bio.

Disturbed sleep in individuals with Idiopathic environmental intolerance attributed to electromagnetic fields (IEI-EMF): Melatonin assessment as a biological marker

著者: Andrianome S, Hugueville L, de Seze R, Hanot-Roy M, Blazy K, Gamez C, Selmaoui B
掲載誌: Bioelectromagnetics 2016; 37 (3): 175-182
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この研究は、電磁界を原因と思う特発性環境不耐性（IEI-EMF）と自己申告した人達（IEI-EMF群n = 30）と過敏症でない対照群（n = 25）を対象に、電磁界へのばく露がない状況下でのメラトニンレベルを比較した。全被験者は主観的睡眠質、睡眠量に関する3つの質問票に記入し、唾液中メラトニンおよびメラトニン尿中代謝物（aMT6s）を定量した。その結果、睡眠スコアにはIEI-EMF群と対照群の間で有意差（IEI-EMF群でのスコア低下）が見られたにも拘わらず、唾液中メラトニンおよび尿中aMT6sでは、両群に統計的有意差は見られなかった、と報告している。

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研究目的（著者による）

The differences between electrosensitive and healthy subjects regarding sleep quality and the melatonin level in saliva and urine should be investigated.

詳細情報

30 electrosensitive and 25 healthy subjects participated in the study. Subjects collected their two first saliva samples at home. The first sample was collected before bedtime on the day prior to the experiment. The second sample was taken 5 min after they woke up in the morning of the experiment day before coming to laboratory. Participants arrived at the laboratory around 09:00 and spent their waking time there. Saliva was then collected every 30 min from 10:00 to 11:30 and from 14:00 to 16:30. Total urine was collected overnight from 20:00 on the previous day to wake-up time as the night fraction, and from wake-up time to 16:30 as the daytime fraction.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1:
  • unspecified
 -

General information

no exposure; during the time in the laboratory, participants were located inside a dimly lit, electrically shielded room serving as a Faraday cage allowing electrosensitive participants to be in an environment without EMFs

ばく露1

主たる特性
周波数
  • unspecified
ばく露装置
パラメータ

No parameters are specified for this exposure.

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:

研究の主なアウトカム（著者による）

The subjective sleep quality was significantly lower in electrosensitive subjects than in healthy subjects, while there were no differences observed in sleepiness.
However, no statistical difference was found between the two groups for saliva melatonin and urine hydroxymelatoninsulfate levels.
The authors conclude that the present results show no association between the melatonin level in saliva and urine and a reduced subjective sleep quality in electrosensitive persons.

研究の種別:

研究助成

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