研究のタイプ: 医学／生物学の研究 (experimental study)

[自発的低周波振動の急性電磁界ばく露による変化] med./bio.

The alteration of spontaneous low frequency oscillations caused by acute electromagnetic fields exposure

著者: Lv B, Chen Z, Wu T, Shao Q, Yan D, Ma L, Lu K, Xie Y
掲載誌: Clin Neurophysiol 2014; 125 (2): 277-286
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この研究は、LET信号電磁界（LET RF-EMF）への急性ばく露による局所的な安静時脳活動の変化の有無をボランティア実験により調べた。18人のボランティアで、LET RF-EMFへのばく露および擬似ばく露セッション（それぞれ30分間）を含む実験を、二重ブラインド、クロスオーバー、無作為化、カウンターバランスして行った。LET RF-EMF発生源は右の耳の近くに置き、ばく露（擬似ばく露）の前と後に脳の安静時fMRIを記録した。自発的脳活動の指標として、自発的ゆらぎの大きさ（ALFF）およびフラクショナルALFF（fALFF）を用いた。その結果、ばく露後、左上側頭回、左中側頭回、右上側頭回、右中前頭回、中心傍小葉の周辺のALFF値の低下が見られた；右中前頭回および中心傍小葉ではfALFFの低下も見られた、と報告している。

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研究目的（著者による）

To investigate the effects of exposure to a Long Term Evolution (LTE) signal on the resting state brain activity in humans.

詳細情報

18 subjects were exposed or sham exposed in 2 sessions (cross-over study). The two sessions were seperated by one day. Functional magnetic resonance imaging (fMRI) was performed before and after the exposure/sham exposure period to measure the resting state brain activity . Additionally, before the exposure/sham exposure period a structural magnetic resonance imaging was performed to determine the specific absorption rate.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 2.573 GHz
ばく露時間: continuous for 30 minutes
  • SAR: 2.18 W/kg maximum (1 g) (subject A)
  • SAR: 2.36 W/kg maximum (1 g) (subject B)
  • SAR: 0.9 W/kg spatial average (10 g) (subject A)
  • SAR: 1.07 W/kg spatial average (10 g) (subject B)

General information

Reference article: IEEE Standard 1528. IEEE recommended practice for determining the peak spatial average specific absorption rate (SAR) in the human head from wireless communications devices: measurement techniques. NJ, USA: Piscataway; 2003.

ばく露1

主たる特性
周波数 2.573 GHz
タイプ
  • electromagnetic field
特性
  • near field
ばく露時間 continuous for 30 minutes
ばく露装置
ばく露の発生源／構造
  • dipole antenna
Distance between exposed object and exposure source 1 cm
ばく露装置の詳細 experiment was carried out in an anechoic chamber; dipole antenna was placed on the right side with a distance of 1 cm to the ear; spacing distance between antenna and ear was restricted by white foam, length of the dipole was perpendicular to the head length, subjects sat comfortably in a chair with touching the foam and were quiet
Sham exposure A sham exposure was conducted.
パラメータ
測定量 値 種別 Method Mass 備考
SAR 2.18 W/kg maximum 測定値 1 g subject A
SAR 2.36 W/kg maximum 測定値 1 g subject B
SAR 0.9 W/kg spatial average 測定値 10 g subject A
SAR 1.07 W/kg spatial average 測定値 10 g subject B

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露前
  • ばく露後

研究の主なアウトカム（著者による）

After exposure, a decreased ALFF amplitude was found in the left and right superior temporal gyrus, in the left middle temporal gyrus, in the right medial frontal gyrus and in the right paracentral lobule in comparison to sham exposure conditions. Additionally, in exposed subjects, a decreased fALFF amplitude was detected in the right medial frontal gyrus and right paracentral lobule compared to sham exposed subjects.
The data indicate that exposure to a Long Term Evolution (LTE) signal modulated the resting state brain activity in humans.

研究の種別:

研究助成

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