[アフリカツメガエルの胚発生に対する900および1800MHzGSMの模擬的無線周波放射とニコチン硫酸塩投与の影響] med./bio.

The effects of an acute exposure of embryos of the African clawed frog to a 900 or 1800 MHz electromagnetic field and co-exposure to nicotine sulfate on the embryonic development should be investigated.

Nicotine sulfate was used as a positive control on the one hand and to investigate the synergistic effects of an electromagnetic field exposure and nicotine on the other hand.
The embryos were divided into the six following groups: 1) no exposure to electromagnetic field + nicotine sulfate (12.5 or 25 ng/ml in the petri dish solution), 2) 900 MHz electromagnetic field with 1 W power + nicotine sulfate (0, 12.5 or 25 ng/ml), 3) 900 MHz electromagnetic field with 2 W power + nicotine sulfate, 4) 1800 MHz electromagnetic field with 1 W power + nicotine sulfate, 5) 1800 MHz electromagnetic field with 2 W power + nicotine sulfate and 6) no exposure to electromagnetic field + no nicotine sulfate (control).
Approximately 120 exposed embryos and ca. 60 control embryos were used in each test and all tests were replicated 3-5 times.

• 動物
• African clawed frog (Xenopus laevis) (embryos)
• 全身

The exposure to the 1800 MHz electromagnetic field (groups 4 and 5 without nicotine sulfate) or nicotine sulfate alone (group 1) resulted in significantly reduced numbers of normally developed tadpoles compared to the control (group 6) with a tendency of enhanced effects with increasing exposure duration and power or concentration, respectively. An exposure to an electromagnetic field and co-exposure to nicotine sulfate (groups 2-5) led to significantly reduced numbers of normally developed tadpoles in all approaches compared to the control with up to 100% mortality in approaches with exposure to the 1800 MHz electromagnetic field and co-exposure to 25 ng/ml nicotine sulfate (groups 4 and 5).
The authors conclude that an acute exposure of embryos of the African clawed frog to a 1800 MHz electromagnetic field can influence the embryonic development and that especially an electromagnetic field exposure and co-exposure to nicotine sulfate can have severe negative effects.