研究のタイプ: 医学／生物学の研究 (experimental study)

[携帯電話からの夕方の電磁波ばく露はその後のメラトニン生成に影響するか？] med./bio.

Does evening exposure to mobile phone radiation affect subsequent melatonin production?

著者: Wood AW, Loughran SP, Stough C
掲載誌: Int J Radiat Biol 2006; 82 (2): 69-76
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この研究は、睡眠の前にデジタル携帯電話のハンドセットからの電磁放射のばく露を受けることがメラトニン分泌に影響するか否かを、ボランティア実験で調べた。二重ブラインド化クロスオーバーデザインで、55人の成人ボランティアは、携帯電話からの電磁放射（平均出力）への30分間のばく露、擬似ばく露を受けた（ランダムな順序で、連続した日曜日の夜に）。尿の採取は、就寝直前と翌朝起床時に行われた。メラトニン分泌量を、主要代謝物濃度（6-スルファトキシメラトニン（aMT6s）：ラジオイムノアッセイで測定）、尿量、およびクレアチニン濃度から推定した。その結果、総メラトニン代謝物分泌量（濃度x尿量）は、ばく露および擬似ばく露条件の間で差がなかった；就寝時間の前と後での分泌量を別個に見ると、ばく露群での就寝前の値は、擬似ばく露群に比べて低値であったが、有意差はなかった；クレアチニン濃度に対するaMT6sの比からメラトニン代謝物分泌量を推定した場合、ばく露群での就寝前の値は、擬似ばく露群に比べ有意に低かった（p = 0.037）；メラトニンの夜間分泌の総量は、携帯電話からの電磁放射によって変化しなかったが、メラトニンの開始時間に影響する可能性がある、と報告している。

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研究目的（著者による）

To study whether exposure to the emissions from a digital mobile phone prior to sleep alters the secretion of melatonin in 55 volunteers.

影響評価項目

ばく露

ばく露 パラメータ
ばく露1: 895 MHz
Modulation type: pulsed
ばく露時間: continuous for 30 min
  • 電力: 0.25 W mean
  • SAR: 0.674 W/kg average over mass (10 g)
  • SAR: 0.11 W/kg maximum (cf. remarks)

ばく露1

主たる特性
周波数 895 MHz
タイプ
  • electromagnetic field
ばく露時間 continuous for 30 min
Modulation
Modulation type pulsed
Duty cycle 12.5 %
Repetition frequency 217 Hz
Additional information

standard GSM signal with no phase modulation nor 26th pulse blanking present
ばく露装置
ばく露の発生源／構造
  • セルラ－電話
チャンバの詳細 Participants were instructed to sit and look at a white screen. Since the laboratory was an extremely quiet environment (purpose-built for sleep studies), a white noise signal was created by turning on the TV receiver tuned to an unused channel in order to mask any residual sound from the handset.
ばく露装置の詳細 A modified digital mobile phone transmitting in 'test mode' was controlled by a laptop computer via a data cable, which was disconnected after the output was set. The mobile phone was attached to a plastic arm mounted on a modified non-metallic welding helmet, and it rested against the subject's right cheek. The phone's loudspeaker circuit was disabled, and wads of plastic foam were placed in the pouch to absorb and eliminate aural cues from the buzzing of circuitry.
Additional information Volunteers were actively or sham exposed in a double-blind cross-over design in random order on successive Sunday nights, immediately prior to retiring to bed, and also prior to the attachment of recording electrodes and other sensors.
パラメータ
測定量 値 種別 Method Mass 備考
電力 0.25 W mean 測定値 - -
SAR 0.674 W/kg average over mass 測定値 10 g -
SAR 0.11 W/kg maximum 測定値 cf. remarks -
Additional parameter details

The peak SAR value was measured in-line with the phone's antenna over the area corresponding to the temporal lobe.

測定および計算の詳細

The power output of the phone was checked by an independent person using a test antenna connected to a power meter before handing it over to the experimenter, who was thus blind to the status of the phone. Phone outputs were also checked by an independent laboratory three times during the project. In addition, Specific Absorption Rate (SAR) measurements were conducted inside a Specific Anthropomorphic Mannequin (SAM) phantom using a precision robot RF Dosimetric Assessment System (DASY4).

ばく露を受けた生物:

方法 影響評価項目／測定パラメータ／方法

研究対象とした生物試料:
研究対象とした臓器系:
調査の時期:
  • ばく露後

研究の主なアウトカム（著者による）

The total overnight melatonin secretion was unaffected by exposure to emissions from a mobile phone for 30 min in the period just prior to sleep. A significant reduction in 6-sulphatoxymelatonin relative to creatinine concentrations in pre-bedtime samples requires indipendent verification.

研究の種別:

研究助成

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