この研究は、Frey and Seifert（1968）が報告した現象（低レベルの平均エネルギー密度のパルス変調マイクロ波照射が、単離されたカエルの心臓に頻脈を引き起こす可能性がある）の検証するために、2種類の実験を実施した。(1) カエル心臓に、in situで、10.0 GHzまたは1.42 GHzのマイクロ波バースト（持続時間100 μs）を照射した。(2) 単離されたカエルの心臓に、1.42 GHzのマイクロ波バースト（持続時間100 μs）を照射した。その結果、どちらの実験においても、マイクロ波パルスの照射による心拍数の有意な変化は観察されなかった、と報告している。
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To examine if pulse modulated microwave exposure is capable to induce tachycardia in frog hearts. The experiments were carried out both in situ and in vitro.
| ばく露 | パラメータ |
|---|---|
|
ばく露1:
1.42 GHz
Modulation type:
pulsed
ばく露時間:
continuous for about 100 s (100 heart beats)
in vivo
|
|
|
ばく露2:
10 GHz
Modulation type:
pulsed
ばく露時間:
continuous for about 100 s (100 heart beats)
in vivo
|
|
|
ばく露3:
1.42 GHz
Modulation type:
pulsed
ばく露時間:
continuous for about 100 s (100 heart beats)
in vitro
|
| 周波数 | 1.42 GHz |
|---|---|
| タイプ |
|
| ばく露時間 | continuous for about 100 s (100 heart beats) |
| Additional information | in vivo |
| Modulation type | pulsed |
|---|---|
| Pulse width | 100 µs |
| Repetition frequency | 1 Hz |
| ばく露の発生源／構造 |
|
|---|---|
| Distance between exposed object and exposure source | 0 mm |
| ばく露装置の詳細 | A semi-rigid 3.58 mm diameter coaxial microprobe delivering the MW energy was lightly pressed against the sinus venosus, i.e. the pacemaker of the frog's heart. |
| Additional information | Two small alligator clips were used for ECG electrodes, one connected on the right side of the neck and the other one on the left thigh. The MW pulse was triggered by the ECG R-wave and was delivered to the heart on the rising phase of the R-wave near its peak. |
| 周波数 | 10 GHz |
|---|---|
| タイプ |
|
| ばく露時間 | continuous for about 100 s (100 heart beats) |
| Additional information | in vivo |
| Modulation type | pulsed |
|---|---|
| Pulse width | 100 µs |
| Repetition frequency | 1 Hz |
| ばく露の発生源／構造 |
|
|---|---|
| Distance between exposed object and exposure source | 0 mm |
| 周波数 | 1.42 GHz |
|---|---|
| タイプ |
|
| ばく露時間 | continuous for about 100 s (100 heart beats) |
| Additional information | in vitro |
| Modulation type | pulsed |
|---|---|
| Pulse width | 100 µs |
| Repetition frequency | 1 Hz |
| ばく露の発生源／構造 |
|
|---|---|
| Distance between exposed object and exposure source | 1 mm |
| ばく露装置の詳細 | The heart was placed ventral side up in a plastic case filled with aerated frog Ringer's solution where it rested lightly on two parallel stainless steel needles used as ECG electrodes. It was positioned with the sinus venosus against a 1-mm thick Lucite window, and the coaxial microprobe was lightly pressed against the outside of the window. |
| Additional information | The MW pulse was triggered either by the ECG P-wave or by the R-wave. |
For both studies, the in situ heart study and the isolated heart study, no significant changes in heart rate were observed.
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