この研究は、永久磁石のどちらかの極の局所的な静磁界が、安静時の皮膚血液灌流に影響するか否かをボランティア実験で調べた。被験者（n = 12）の非利き手の第2指および第4指の甲側皮膚の皮膚血液灌流（SBF）をレーザードップラー法で測定した。どちらに指での実験においても、まず、両方の指に擬似磁石によるばく露を行い、次にネオジム磁石のN極およびS極によるばく露を交互に行なった。ばく露の強度は、その指の手掌部で4024 G、指の甲側のSBF測定点で879±52 Gであった。3通り（擬似、N極、S極）のばく露時間はそれぞれ15分で、各15分のうちの最後の5分間について平均したSBFをSBF値とした。結果として、指を変えて反復測定したSBF値をテスト変数に用いて、磁石の影響または磁極の影響を分散分析した結果、被験者間でSBFに大きなばらつきがあった；ばく露条件間でSBFに有意差はなかった（P = 0.705）；また、SBFと指の間に、有意な交互作用が認められた（P = 0.396）。一方、３つのばく露時間におけるばく露を受ける指と受けない指の間でのSBFの差をテスト変数に用いることで被験者間の変動を低減させた結果、磁石のばく露に起因する有意な影響が示された（P = 0.016）；この影響は、ばく露を受けた指の安静時SBFを減少させるもので、N極およびS極のどちらでの同様であった、と報告している。
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To investigate whether either pole of a local static magnetic field of a permanent magnet affects skin microcirculation.
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| ばく露時間 | 15 min |
| ばく露の発生源／構造 |
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| ばく露装置の詳細 | All testing was done with subjects seated with their arms and hands resting on a padded surface attached to the chair. The top surface of the magnets were covered with soft Velcro material (used for thermal insulation) on which the fingers were resting. |
| Additional information | For sham control non-magnetized pieces of the same dimensions as the magnet, were placed under the middle phalanges of the 2nd and 4th fingers during a 15-min control interval. Thereafter, both shams were removed and replaced with a sham for the 4th finger and an active magnet with either its North or South pole facing the skin of the 2nd finger. Selection of the pole to place during this interval was decided based on a coin flip. After 15 min of exposure, sham and magnet were removed and replaced with a second sham under the 4th finger and the magnet with the opposite polarity under the 2nd finger during a final 15-min interval. In six subjects, the North pole was placed during the second interval, and in six other subjects it was placed during the third interval. |
The results revealed a large variability in finger skin blood perfusion among subjects and no significant difference in skin blood flow between exposure conditions or any significant interaction between skin blood perfusion and finger.
Comparing skin blood perfusion of the magnet-exposed second finger compared to the sham-exposed fourth finger for each subject, exposure to magnet resulted in a reduction in 11 of 12 subjects. There was no significant difference between effects of north and south poles of the magnet.
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