Study type:
Epidemiological study
(observational study)
Magnetic fields exposure and childhood leukemia risk: a meta-analysis based on 11,699 cases and 13,194 controls
epidem.
By:
Zhao L, Liu X, Wang C, Yan K, Lin X, Li S, Bao H, Liu X
Published in: Leuk Res 2014; 38 (3): 269-274
Aim of study (acc. to author)
The association between magnetic field exposure of power lines and the childhood leukemia risk was investigated in a meta-analysis. Following nine studies were included: Michaelis et al, 1997 (Germany), Linet et al, 1997 (USA), Dockerty et al, 1998 (New Zealand), McBride et al, 1999 (Canada), Green et al, 1999 (Canada), Schüz et al, 2001 (Germany), Kabuto et al, 2006 (Japan), Kroll et al, 2010 (UK), and Malagoli et al, 2010 (Italy).
Endpoint/type of risk estimation
Type of risk estimation:
(odds ratio (OR))
Exposure
Assessment
Exposure groups
Group
|
Description
|
Reference group 1
|
magnetic field strength: < 0.1 µT
|
Group 2
|
magnetic field strength: 0.1-0.2 µT
|
Group 3
|
magnetic field strength: 0.2-0.4 µT
|
Group 4
|
magnetic field strength: ≥ 0.4 µT
|
Reference group 5
|
magnetic field strength: < 0.2 µT
|
Group 6
|
magnetic field strength: ≥ 0.2 µT
|
Reference group 7
|
magnetic field strength: < 0.1 µT
|
Group 8
|
magnetic field strength: 0.1-0.2 µT
|
Group 9
|
magnetic field strength: 0.2-0.3 µT
|
Group 10
|
magnetic field strength: ≥ 0.3 µT
|
Population
-
Group:
-
Age:
0–15 years
-
Observation period:
1962 - 2007
-
Study location:
USA, Canada, UK, Germany, Italy, Japan, New Zealand
Study size
Other:
11,699 cases and 13,194 controls
Statistical analysis method:
- heterogeneity analysis, Funnel plot, Egger's test
Results (acc. to author)
Study funded by
-
Department of Health of Jilin Province, China
-
Fundamental Research Funds for the Jilin University, China
-
Major State Basic Research Development Program, China
-
National Natural Science Foundation (NSFC), China
-
Postdoctoral Scientific Research Project of Jilin Province, China
-
Program of New Century Excellent Talents in University of China
-
Research Fund for the Doctoral Program of Higher Education, China
Comments on this article
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Valera ET et al.
(2014):
Electromagnetic fields at extremely low frequencies and the risk for childhood leukemia: do we have enough information to warrant this association?
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Olsen J et al.
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Myers A et al.
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