To study if exposure used in mobile phones and wireless network technologies would induce DNA damage in cultured human lymphocytes (from six smoking or non-smoking donors) with and without clastogen mitomycin C (co-exposure) for one full cell cycle.
In some cell cultures DNA synthesis (hydroxyurea) and DNA repair (caffeine) were inhibited. Positive controls and negative controls were included in each experiment.
Exposure | Parameters |
---|---|
Exposure 1:
2.3 GHz
Modulation type:
pulsed
Exposure duration:
one cell cycle
|
|
Exposure 2:
2.3 GHz
Modulation type:
CW
Exposure duration:
one cell cycle
|
|
Frequency | 2.3 GHz |
---|---|
Type | |
Exposure duration | one cell cycle |
Modulation type | pulsed |
---|---|
Duty cycle | 50 % |
Repetition frequency | 200 Hz |
Exposure source | |
---|---|
Distance between exposed object and exposure source | 1.2 m |
Chamber | 5 m x 4 m x 4 m anechoic chamber |
Setup | rectangular horn antennas with an aperture of 6 cm x 8 cm placed facing upward under the samples; |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
power density | 10 W/m² | average over time | measured | - | - |
Frequency | 2.3 GHz |
---|---|
Type | |
Exposure duration | one cell cycle |
Modulation type | CW |
---|
Exposure source |
|
---|
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
power density | 10 W/m² | average over time | measured | - | - |
electric field strength | 61 V/m | - | - | - | - |
No statistically significant differences were found between control and exposed cultures with or without mitomycin C, for any of the chromosomal parameters for any of the donors in the uninhibited assay or in the cell cultures where DNA synthesis and DNA repair were inhibited.
A weak trend towards more chromosomal damage from pulsed wave rather than continuous wave exposure was observed as well as a weak trend for more chromosomal damage with the interaction of pulsed electromagnetic fields with mitomycin C (compared to a continuous wave exposure).
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