The effects of a prenatal and postnatal exposure of rats to a 950 MHz electromagnetic field on oxidative damages of DNA, proteins and lipids in the cortex should be investigated.
Pregnant rats were divided into two groups (exposure and sham exposure, n=6 each) and were (sham) exposed from the first day of pregnancy until up to 6 days after birth of the pups. Directly after birth and 6 days thereafter, 6 pups from exposed dams and 6 pups from sham exposed dams were killed and investigated, respectively.
Exposure | Parameters |
---|---|
Exposure 1:
950 MHz
Exposure duration:
continuous for 30 min/day from the first day of gestation until birth
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Exposure 2:
950 MHz
Exposure duration:
continuous for 30 min/day from the first day of gestation until 6 days after birth
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further exposure reference: Sadiku, 2010: Elements of electromagnetics. 5th edition. London, UK: Oxford University Press.
Frequency | 950 MHz |
---|---|
Type | |
Exposure duration | continuous for 30 min/day from the first day of gestation until birth |
Additional info | vertical polarization |
Exposure source | |
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Chamber | polypropylene boxes (40.5 x 33.3 x 17.5 cm) |
Setup | boxes were placed 11 cm away from the antenna; exposure system was kept in an aluminium Faraday cage (101.5 x 64.0 x 38.0 cm; 0.5 cm mesh); cages were placed on a wooden tray |
Sham exposure | A sham exposure was conducted. |
Additional info | the cage with the sham-exposed group was placed 92 cm away from the cage of the exposure group |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
electric field strength | 35 V/m | spatial average | measured | - | - |
electric field strength | 52.1 V/m | maximum | measured | - | - |
electric field strength | 13.5 V/m | minimum | measured | - | - |
power | 1 W | - | - | - | - |
SAR | 1.32 W/kg | - | calculated | - | for pups on day of birth |
electric field strength | 32.8 V/m | - | calculated | - | internal electric field in the brain of newborn rats |
SAR | 0.44 W/kg | - | calculated | - | for dams on first day of gestation |
Frequency | 950 MHz |
---|---|
Type | |
Exposure duration | continuous for 30 min/day from the first day of gestation until 6 days after birth |
Additional info | vertical polarization |
Exposure source |
|
---|---|
Sham exposure | A sham exposure was conducted. |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
electric field strength | 35 V/m | spatial average | measured | - | - |
electric field strength | 52.1 V/m | maximum | measured | - | - |
electric field strength | 13.5 V/m | minimum | measured | - | - |
power | 1 W | - | - | - | - |
SAR | 1.14 W/kg | - | calculated | - | for pups on day 6 of birth |
SAR | 0.35 W/kg | - | calculated | - | for dams on day 6 after birth |
electric field strength | 33.8 V/m | - | calculated | - | internal electric field in brain of 6 day old pups |
Newborn rats from exposed dams had a significantly reduced body weight in comparison to rats from sham exposed dams.
6-day-old exposed rats showed a significantly higher amount of carbonyl proteins in the right cortex and a significantly lower blood glucose level compared to the sham exposure group.
All other parameters did not show any significant differences between the exposure groups and the respective sham exposure groups.
The authors conclude that a prenatal and postnatal exposure of rats to a 950 MHz electromagnetic field does not seem to induce oxidative damages of DNA, proteins and lipids in the cortex.
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