To study the effect of radiofrequency exposure on the permeability of the blood-brain barrier in male and female rats.
The right hemisphere, left hemisphere, cerebellum, and total brain were analyzed separately.
The animals were divided into six groups (n=9 per proup): 1) sham exposed female rats, 2) sham exposed male rats, 3) 0.9 GHz exposed females 4) 0.9 GHz exposed males, 5) 1.8 GHz exposed females, 6) 1.8 GHz exposed males.
Exposure | Parameters |
---|---|
Exposure 1:
0.9 GHz
Modulation type:
CW
Exposure duration:
continuous for 20 min
|
|
Exposure 2:
1.8 GHz
Modulation type:
CW
Exposure duration:
continuous for 20 min
|
|
The animals were treated in the following six groups: i) female sham exposure ii) male sham exposure iii) female exposure to 0.9 GHz iv) male exposure to 0.9 GHz v) female exposure to 1.8 GHz vi) male exposure to 1.8 GHz
Frequency | 0.9 GHz |
---|---|
Type | |
Exposure duration | continuous for 20 min |
Modulation type | CW |
---|
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
electric field strength | 4.71 V/m | - | - | - | ± 0.02 V/m |
SAR | 4.26 mW/kg | average over mass | calculated | 10 g | brain tissue |
Frequency | 1.8 GHz |
---|---|
Type | |
Exposure duration | continuous for 20 min |
Modulation type | CW |
---|
Exposure source |
|
---|---|
Distance between exposed object and exposure source | 10 cm |
Sham exposure | A sham exposure was conducted. |
Measurand | Value | Type | Method | Mass | Remarks |
---|---|---|---|---|---|
electric field strength | 4.92 V/m | - | - | - | ± 0.12 V/m |
SAR | 1.46 mW/kg | average over mass | calculated | 10 g | brain tissue |
No albumin extravasation was found in the brains of female rats after radiofrequency exposure. However, a significant increase in albumin extravasation was found in the brains of the exposed male rats when compared to sham exposed male animals.
These data suggest that 0.9 and 1.8 GHz radiofrequency exposure (continuous wave) at levels below the international limits can affect the vascular permeability in the brain of male rats.
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