To analyze the immediate and late effects of 4 h microwave exposure on the permeability of the blood-brain barrier using a novel exposure system which simulates the absorption characteristics of cellular phones operating in the 900 MHz frequency band in the heads of rats maintained in a fixed position in relation to the antenna.
| Frequency | 900 MHz |
|---|---|
| Type | |
| Exposure duration | continuous for 4 h |
| Modulation type | pulsed |
|---|---|
| Repetition frequency | 217 Hz |
| Exposure source |
|
|---|---|
| Chamber | Plexiglas carousel |
| Setup | Rats were restrained in plastic tubes mounted circularly in a Plexiglas carousel with the head towards the antenna. |
| Additional info | As negative control two groups were used: a freely moving control group and a sham exposed group which was restrained for 4 h in the exposure system. As positive controls, focal BBB disturbances were produced in two rats by cold injury. |
The increase in serum albumin extravasations after microwave exposure reached significance only in the group exposed to the highest SAR of 7.5 W/kg. Histological injury was not observed in any of the examined brains. The study demonstrates that microwave irradiation in the frequency and intensity range of mobile telephony is unlikely to produce pathologically significant changes of the blood-brain barrier permeability.
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