Exposure to 2.45 GHz microwave radiation provokes cerebral changes in induction of HSP-90 a/ß.heat shock protein in rat med./bio.

Aim of study (acc. to author)

Background/further details

Endpoint

• effects on the neurological system: level and distribution of heat shock protein (Hsp90) in the brain neuron degeneration: "dark neurons", cell nucleus morphology

Exposure

• • 2.45 GHz
  • 2.45 GHz
  • microwaves
• • CW continuous wave

Extended view Compact view

Methods Endpoint/measurement parameters/methodology

• molecular biosynthesis: Hsp90 expression (see "effects on the neurological system")
• effects on the neurological system: level and distribution of Hsp90 (Bradford protein assay, ELISA and immunohistochemistry); neuron degeneration: number of "dark neurons" (toluidine blue staining, light microscopy, semiquantitative estimation), cell nucleus morphology (DAPI staining, fluorescence microscopy)

Main outcome of study (acc. to author)

Study funded by

• Ministerio de Educacion (Ministry of Education), Spain
• Secretariat General for Research and Development of the Xunta de Galicia, Spain
• Xunta de Galicia, Spain

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