Study type: Medical/biological study (experimental study)

Effects of static and ELF magnetic fields on free-radical processes in rat liver and kidney med./bio.

Published in: Electro Magnetobiol 2000; 19 (1): 99-105

Aim of study (acc. to author)

To study the activities of the antioxidant enzymes superoxide dismutase, catalase, and glutathione peroxidase and the levels of malondialdehyde in the liver and kidneys of male and female rats (n=40) exposed to static magnetic fields and extremely low frequency magnetic fields.

Endpoint

Exposure

Exposure Parameters
Exposure 1:
Exposure duration: 2 h/day for 20 days
Exposure 2: 50 Hz
Exposure duration: 2 h/day for 20 days

General information

experimental groups: 2 groups of 20 female rats and two groups of 20 male rats control groups: 1 group of 20 female rats, 1 group of 20 male rats

Exposure 1

Main characteristics
Frequency
Type
Exposure duration 2 h/day for 20 days
Exposure setup
Exposure source
Chamber exposure chamber: 22 x 22x 22 cm centered between the electromagnet poles.
Setup The animals were placed in well ventillated Plexiglas holder restraining tubes (17 cm in length, 11.5 cm in diameter).
Additional info Control animals were treated in the same way but were not exposed to MF.
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.49 T - measured - non-linear MF with 0-2 T/m gradient

Exposure 2

Main characteristics
Frequency 50 Hz
Type
Waveform
Exposure duration 2 h/day for 20 days
Exposure setup
Exposure source
Parameters
Measurand Value Type Method Mass Remarks
magnetic flux density 0.018 T - measured - -

Exposed system:

Methods Endpoint/measurement parameters/methodology

Investigated system:
Investigated organ system:
Time of investigation:
  • after exposure

Main outcome of study (acc. to author)

Extremely low frequency magnetic fields increased all enzyme activities and malondialdehyde levels in both the liver and kidneys. In contrast, static magnetic field did not produce changes.
The data indicate that extremely low frequency magnetic fields affect free radical processes in the liver and kidney.

Study character:

Study funded by

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