This study was designed to investigate whether effects of extremely low frequency magnetic fields on malondialdehyde level and myeloperoxidase activity can be appropiately analysed and formulated by a computer method.
A total of 54 male, 250-300 grams weighted, 10-12 weeks old, guiena pigs were used. Experimental results were compared to the results calculated by use of genetic programming (GP). Genetic programming belongs to evolutionary algorithms based on the principles of genetics and natural selections. It can be applid when biological effects are not measurable precisely as in this study the myeloperoxidase activity.
Exposure | Parameters |
---|---|
Exposure 1:
50 Hz
Exposure duration:
4 h/day or 8 h/day for 5 days
|
|
Frequency | 50 Hz |
---|---|
Type | |
Exposure duration | 4 h/day or 8 h/day for 5 days |
Exposure source | |
---|---|
Setup | animals in 26 cm x 22 cm x 10 cm plastic cages in the center of the coil |
Sham exposure | A sham exposure was conducted. |
Measurand | Value | Type |
---|---|---|
magnetic flux density | 1 mT | minimum |
magnetic flux density | 2 mT | - |
magnetic flux density | 3 mT | maximum |
It was found that genetic programming showed high accuracy and can be therefore effectively used to model malondialdehyde level and myeloperoxidase activity.
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