To study the erythropoietic changes in rats subchronically exposed to radiofrequency microwave irradiation at nonthermal levels.
The exposed group (n=40) was divided in 4 subgroups (each n=10) that were exposed 2, 8, 15 or 30 days. The unexposed group (n=24) serving as control was divided in 4 subgroups (n=6 each) to be sacrificed on experimental days 2, 8, 15 or 30
| Frequency | 2.45 GHz |
|---|---|
| Charakteristic | |
| Exposure duration | repeated daily exposure, 2 h/day for 2, 8, 15 or 30 days |
| Additional info | Reference article: World Health Organization (WHO): Electromagnetic fields (300 Hz to 300 GHz). In: Environmental Health Criteria 137. Geneva: World Health Organization 1993 |
| Modulation type | CW |
|---|
| Exposure source |
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|---|---|
| Distance between exposed object and exposure source | 1.4 m |
| Setup | The rats were placed in individual Plexiglas cages and were kept in a controlled environment at 22°C with 12 h ligh/dark. |
| Measurand | Value | Type | Method | Mass | Remarks |
|---|---|---|---|---|---|
| power density | 50 W/m² | mean | measured | - | to 100 W/m², corresponding to an approximate SAR 1-2 W/kg for middle sized rat |
In the exposed rats erythrocyte count, haemoglobin and hematocrit were increased in peripheral blood on irradiation days 8 and 15. Anuclear cells and erythropoietic cells were significantly decreased in the bone marrow on day 15, but micronucleated cells' frequency was increased.
Under these experimental conditions, microwave irradiation caused disturbance in red blood cell maturation and proliferation, and induced micronucleus formation in erythropoietic cells.
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